Central Nervous System Lymphoma: Characteristic Findings on Traditional and Advanced Imaging
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TLDR
New CT and MR imaging techniques and metabolic imaging have demonstrated characteristic findings in CNS lymphoma, aiding in its differentiation from other CNS lesions, and advanced imaging techniques may, in the future, substantially improve the diagnostic accuracy of imaging, ultimately facilitating a noninvasive method of diagnosis.Abstract:
CNS lymphoma consists of 2 major subtypes: secondary CNS involvement by systemic lymphoma and PCNSL. Contrast-enhanced MR imaging is the method of choice for detecting CNS lymphoma. In leptomeningeal CNS lymphoma, representing two-thirds of secondary CNS lymphomas, imaging typically shows leptomeningeal, subependymal, dural, or cranial nerve enhancement. Single or multiple periventricular and/or superficial contrast-enhancing lesions are characteristic of parenchymal CNS lymphoma, representing one-third of secondary CNS lymphomas and almost 100% of PCNSLs. New CT and MR imaging techniques and metabolic imaging have demonstrated characteristic findings in CNS lymphoma, aiding in its differentiation from other CNS lesions. Advanced imaging techniques may, in the future, substantially improve the diagnostic accuracy of imaging, ultimately facilitating a noninvasive method of diagnosis. Furthermore, these imaging techniques may play a pivotal role in planning targeted therapies, prognostication, and monitoring treatment response.read more
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References
More filters
Journal ArticleDOI
Primary intracerebral malignant lymphoma: report of 248 cases.
Benoit Bataille,Vincent Delwail,Emmanuelle Menet,Pierre Vandermarcq,Pierre Ingrand,Michel Wager,Guy G,Francoise Lapierre +7 more
TL;DR: This European survey provides a reasonable basis for the treatment of primary intracerebral lymphoma with the following sequence: stereotactic biopsy sampling, chemotherapy with a methotrexate- and anthracycline-based regimen, followed by cranial irradiation.
Journal ArticleDOI
Primary central nervous system lymphoma.
TL;DR: The differential diagnosis of PCNSL includes central nervous system gliomas, metastatic tumors, demyelinating disorders, subacute infarcts, and space-occupied lesions due to an infectious etiology.
Journal ArticleDOI
Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy
TL;DR: This work states that IO nanoparticles possess unique paramagnetic properties, which and generate significant susceptibility effects resulting in strong T2 and T2* contrast, as well as T1 effects at very low concentrations for magnetic resonance imaging (MRI), which is widely used for clinical oncology imaging.
Journal ArticleDOI
Primary Central Nervous System Lymphoma
Howard A. Fine,Robert J. Mayer +1 more
TL;DR: The findings suggest that primary central nervous system lymphoma in patients with AIDS has a significantly different natural history than it does in immunocompetent persons.
Journal ArticleDOI
Changes in AIDS-related lymphoma since the era of highly active antiretroviral therapy
Caroline Besson,Aicha Goubar,Jean Gabarre,Willy Rozenbaum,Gilles Pialoux,François-Patrick Châtelet,Christine Katlama,Frédéric Charlotte,Bertrand Dupont,Nicole Brousse,Michel Huerre,Jacqueline Mikol,Philippe Camparo,Karima Mokhtari,Micheline Tulliez,Dominique Salmon-Ceron,Boue F,Dominique Costagliola,Martine Raphael +18 more
TL;DR: The profile of ARL has changed since the era of HAART, with a lower incidence of systemic and brain ARL, and the prognosis of systemic ARl has improved.