Challenges & options in dengue prevention & control: A perspective from the 2015 outbreak.
Siddharth Jain,Surendra K Sharma +1 more
TLDR
The menace of dengue has reached pandemic proportions and become a major public health concern, and the worst affected are the WHO South-East Asia region (SEAR) and Western Pacific regions.Abstract:
The menace of dengue has reached pandemic proportions and become a major public health concern. It has emerged and re-emerged across the globe to cause larger, more frequent and severe outbreaks involving areas thus far unaffected. As per the World Health Organization (WHO) fact sheet, dengue is endemic in >100 countries with 50 per cent of the world population at risk1. The true global burden of dengue is still uncertain, and the incidence may be as high as 390 million infections per year as opposed to the WHO estimates of 50-100 million, due to lack of surveillance and under-reporting2. The worst affected are the WHO South-East Asia region (SEAR) and Western Pacific regions.read more
Citations
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Spinal tuberculosis: review of current management.
Robert Dunn,M Ben Husien +1 more
TL;DR: This review discusses the epidemiology, clinical presentation, diagnosis, impact of HIV and both the medical and surgical options in the management of spinal TB.
Journal ArticleDOI
Antivirus effectiveness of ivermectin on dengue virus type 2 in Aedes albopictus.
TL;DR: Generally, DENV-2 replicated well in Aedes albopictus without ivermectin intervention, whose virus loads exhibited significantly higher when the mosquitoes were holding from 4 days to 10 days after infectious blood feeding, whereas with the treatment of iverMectin, the infection rate was reduced by as much as 49.63%.
Journal ArticleDOI
Clinical and Hematological Profile of Patients with Dengue Fever at a Tertiary Care Hospital – An Observational Study
TL;DR: Most of DF cases can be managed on OPD basis and SD with severe bleeding or with severe plasma leakage carries high mortality, which can analyze annual data for resource allocation for capacity expansion.
Journal ArticleDOI
Use of steroids for abdominal tuberculosis: a systematic review and meta-analysis
Hariom Soni,Balaji L Bellam,Raghavendra K Rao,Praveen M Kumar,Harshal S Mandavdhare,Harjeet Singh,Usha Dutta,Vishal Sharma +7 more
TL;DR: Although steroids seem to have some benefit in patients of tubercular peritonitis, the poor quality of studies limits the generalisability of the findings.
References
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Journal ArticleDOI
The global distribution and burden of dengue
Samir Bhatt,Peter W. Gething,Oliver J. Brady,Jane P. Messina,Andrew Farlow,Catherine L. Moyes,John M. Drake,John M. Drake,John S. Brownstein,Anne G. Hoen,Osman Sankoh,Osman Sankoh,Monica F. Myers,Dylan B. George,Thomas Jaenisch,G. R. William Wint,Cameron P. Simmons,Thomas W. Scott,Thomas W. Scott,Jeremy Farrar,Jeremy Farrar,Simon I. Hay,Simon I. Hay +22 more
TL;DR: These new risk maps and infection estimates provide novel insights into the global, regional and national public health burden imposed by dengue and will help to guide improvements in disease control strategies using vaccine, drug and vector control methods, and in their economic evaluation.
Book
The Government of India
TL;DR: The National Policy on Open Standards for e- Governance provides a set of guidelines for the uniform and reliable implementation of e-Governance solutions to ensure seamless interoperability of various solutions developed by multiple agencies.
Journal ArticleDOI
Treatment of substance use disorders through the government health facilities: Developments in the “Drug De-addiction Programme” of Ministry of Health and Family Welfare, Government of India
TL;DR: Monitoring and evaluation exercises carried out show that the existing model of inpatient treatment and of shared responsibility between central and state governments is partially successful, and the establishment of drug treatment clinics on pilot basis with a focus on outpatient treatment and direct support from the DDAP is showing encouraging results.
Journal ArticleDOI
Control of Mosquito-Borne Infectious Diseases: Sex and Gene Drive
Zach N. Adelman,Zhijian Tu +1 more
TL;DR: More advanced technologies at driving maleness, the ultimate disease refractory phenotype, become possible and may represent efficient and self-limiting methods to control mosquito populations.
Journal ArticleDOI
Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority trial
David C. Lye,David C. Lye,Sophia Archuleta,Sophia Archuleta,Sharifah F Syed-Omar,Jenny G. Low,Jenny G. Low,Helen M. L. Oh,Helen M. L. Oh,Yuan Wei,Dale Fisher,Dale Fisher,Sasheela Ponnampalavanar,Limin Wijaya,Linda K. Lee,Eng Eong Ooi,Adeeba Kamarulzaman,Lucy Chai See Lum,Paul Ananth Tambyah,Paul Ananth Tambyah,Yee Sin Leo +20 more
TL;DR: In adult patients with dengue and thrombocytopenia, prophylactic platelet transfusion was not superior to supportive care in preventing bleeding, and might be associated with adverse events.