Journal ArticleDOI
Chromosomal and nucleolar RNA synthesis in root tips during mitosis.
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Comparative rates of RNA synthesis in chromatin and nucleolar fractions during mitosis in root-tip cells of Allium and Nigella were studied by pulse-labeling of cells with tritiated cytidine.Abstract:
Comparative rates of RNA synthesis in chromatin and nucleolar fractions during mitosis in root-tip cells of Allium and Nigella were studied by pulse-labeling of cells with tritiated cytidine. Although the rate of RNA synthesis decreases in the condensing chromosomes during prophase, it remains normal in the nucleolar fraction as long as nucleoli are maintained. RNA synthesis stops in mitotic cells lacking distinct nucleoli. In the late telophase or very early interphase cells, RNA synthesis resumes at a faster rate in the pronucleolar bodies than in the chromatin.read more
Citations
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Journal ArticleDOI
Synthetic activities during spermatogenesis in the mouse, rna and protein.
TL;DR: A number of evidences suggest that this “arginine-rich” spermatid histone is effectively synthesized within the nucleus, although the alternative interpretation of a cytoplasmic synthesis followed by transfer of the newly synthesized histone into the nucleus cannot be actually rejected.
Journal Article
The relationship of the cell cycle to tumor growth and control of cell division: a review.
TL;DR: Although the length of the cell cycle varies in different kinds of cells, it is shorter in certain cells of the adult animal than in some of the fastest growing tumors, so tumor growth must involve other kinetic parameters besides speed of cell proliferation.
Book ChapterDOI
The nucleolus and the synthesis of ribosomes.
TL;DR: The role of the nucleolus in the synthesis of ribosomal RNA (rRNA) is discussed in this article, where the authors discuss various lines of evidence that have been linked with ribosome synthesis, trying, where possible, to indicate the limitations of current concepts.
Journal ArticleDOI
Differential rate of ribonucleic acid synthesis in the autosomes and sex chromosomes during male meiosis in the mouse.
TL;DR: A working hypothesis is forwarded to account for the absence or scarcity of RNA synthesis during early meiotic prophase.
Journal ArticleDOI
RNA synthesis during male meiosis and spermiogenesis
TL;DR: Using 3H-uridine, the course of RNA synthesis has been followed autoradiographically during all stages of male meiosis and spermiogenesis in the locusts Schistocerca gregaria and Cyrtacanthacris tartarica and the grasshopper Chorthippus brunneus.
References
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Journal ArticleDOI
Synthesis of RNA and protein during mitosis in mammalian tissue culture cells.
D.M. Prescott,M.A. Bender +1 more
TL;DR: The capacity of these cells to incorporate 3 H histidine appeared to decline as the duration of metaphase arrest increased, and the transfer of RNA from nucleus to cytoplasm was faster for the more rapidly growing hamster cells than for HeLa.
Journal ArticleDOI
Nucleic acid synthesis in relation to the cell division cycle
TL;DR: By the use of autoradiography and tritium-labeled nucleosides of high speif ic activity, especially with cells in sterile culture, a more critical analysis of the cyclic changes in RNA synthesis is now possible.
Journal ArticleDOI
Nucleic acid and protein metabolism during the mitotic cycle in Vicia faba.
TL;DR: The autoradiographic data and the microphotometric data indicate that the mitotic cycle may be divided into several metabolic phases, three predominantly anabolic (net increase), and a fourth phase predominantly catabolic (nets decrease).
Journal ArticleDOI
RNA and DNA metabolism in human tissue culture cells studied with tritiated cytidine.
TL;DR: The experimental results lend support to the hypothesis that RNA synthesis begins in the chromatin portion of the nucleus, and it is confirmed for HeLa cells that cytidine is in part converted to thymidine for DNA synthesis and uridine for RNA synthesis.
Journal ArticleDOI
A study of nucleic acid synthesis in ascites tumor cells by two-emulsion autoradiography
TL;DR: The present communicat ion reports studies on the timing of R N A synthesis during the mitotic cycle of the Ehrlich ascites tumor cell.
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