Journal ArticleDOI
Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study
E. Tarín-Vicente,Andrea Alemany,M. Agud‐Dios,María Ubals,Clara Suñer,Andrés Antón,Maider Arando,Jorge Arroyo-Andrés,L. Calderón-Lozano,Cristina Casañ,José Miguel Cabrera,Pep Coll,Vicente Descalzo,María Dolores Folgueira,Jorge N. Garcia-Pérez,Elena Gil-Cruz,B. González Rodríguez,C. Gutiérrez-Collar,Agueda Hernandez-Rodriguez,Paula López-Roa,María de los Ángeles Meléndez,J. Montero-Menárguez,Irene Muñoz-Gallego,Sara Isabel Palencia-Pérez,Roger Paredes,Alfredo Pérez-Rivilla,Maria Piñana,Nuria Prat,Aida Contreras Ramírez,Ángel J. Gordillo Rivero,C.A. Rubio‐Muniz,Marti Vall,Kevin Stephen Acosta-Velásquez,An-liu Wang,Cristina Galván-Casas,Michael Marks,Pablo L. Ortiz-Romero,Oriol Mitjà +37 more
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TLDR
In this cohort, monkeypox caused genital, perianal, and oral lesions and complications including proctitis and tonsillitis, which suggests close contact is probably the dominant transmission route in the current outbreak.About:
This article is published in The Lancet.The article was published on 2022-08-01. It has received 255 citations till now. The article focuses on the topics: Medicine.read more
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Journal ArticleDOI
HIV and Sexually Transmitted Infections Among Persons with Monkeypox — Eight U.S. Jurisdictions, May 17–July 22, 2022
Kathryn G. Curran,Kristen Eberly,Olivia Ollinger Russell,Robert E. Snyder,Elisabeth K. Phillips,Eric C Tang,Philip J. Peters,Melissa Sanchez,Ling Hsu,Stephanie E. Cohen,Ekow Kwa Sey,Sherry Yin,Chelsea Foo,William Still,Anil T. Mangla,Brittani Saafir-Callaway,Lauren Barrineau-Vejjajiva,Cristina Meza,E. Burkhardt,Patricia Aikins Murphy,Nora K Kelly,Hillary Spencer,Irina Tabidze,Massimo Pacilli,Carol-Ann E. Swain,Kathleen M. Bogucki,Charlotte DelBarba,Deepa T Rajulu,Andre Dailey,Jessica N. Ricaldi,Leandro Mena,Demetre Daskalakis,Laura H. Bachmann,John T. Brooks,Alexandra M. Oster,Michael Abassian,M. Abrego,David Addo,Bridget J. Anderson,Connie Austin,Kailey Bradley,David Pham Bui,Shua J Chai,Eric G. Chapman,Joseph P. Clement,Catherine Comis,Phoebe Danza,Marisa Anne Pella Donnelly,Kerri Dorsey,Karen Drezner,Alicia Dunajcik,Areesh Fatmee,Amanda Feldpausch,Lauren E Finn,Rebecca Fisher,Kameron Gadawski,Jasmine Gaillard,Varun Gandhi,Amy B. Garlin,Sarah Gillani,Jamilla Green,Megan Hill,Taylor Holly,Virginia Hu,Otto J Ike,Anna Satcher Johnson,Kelly Johnson,Janna L. Kerins,David A. Kern,Bita Khoshhal,Akiko Kimura,Irma Kocer,Colin Korban,Chun-Mai Kuo,Rodriques Lambert,Issa Lee-Hall,Jessica Lorenzo-Luaces,Elise Mara,Amy Marutani,K. M. Miletti,Wilson P. Miranda,Allison Morrow,D. F. Nims,Melissa Ongpin,Chisom Onyeuku,Jessica Pavlick,Eugene Pennisi,Neela Persad,Mary Pomeroy,Kathleen Poortinga,Dylan Atchley Procter,Marisa Ramos,Eli S. Rosenberg,Lori Saathoff-Huber,Nannie Song,Daniel M. Stowell,Deanna L. Sykes,Amanda Terminello,Ebony S Thomas,Christopher Toomey,Brittany Wilbourn,Tanya Williams,Pascale M. Wortley +102 more
TL;DR: It is important that public health officials leverage systems for delivering HIV and STI care and prevention to reduce monkeypox incidence in this population and consideration should be given to prioritizing persons with HIV infection and STIs for vaccination against monkeypox.
letters-and-commentsDOI
Evidence of human-to-dog transmission of monkeypox virus
Sophie Seang,Sonia Burrel,Eve Todesco,Valentin Leducq,Gentiane Monsel,Diane Le Pluart,Christophe Cordevant,Valérie Pourcher,Romain Palich +8 more
Journal ArticleDOI
Monkeypox: epidemiology, pathogenesis, treatment and prevention
Yong Huang,Li Mu,Wei Wang +2 more
TL;DR: In this paper , the authors reviewed the epidemiology of monkeypox, monkeypox virus reservoirs, novel transmission patterns, mutations and mechanisms of viral infection, clinical characteristics, laboratory diagnosis and treatment measures.
Journal ArticleDOI
Efficacy and safety of Paxlovid for COVID-19:a meta-analysis
Qian Zheng,Pengfei Ma,Ming-Wei Wang,Yongran Chen,Mengyun Zhou,L. Ye,Zhan-Hui Feng,Chun-Lin Zhang +7 more
TL;DR: Wang et al. as discussed by the authors performed a meta-analysis of Paxlovid in patients with COVID-19 and reported a case of COVID19 rebound in a severe COVID 19 patient during long term (20 days) treatment.
Journal ArticleDOI
Assessing Healthcare Workers’ Knowledge and Their Confidence in the Diagnosis and Management of Human Monkeypox: A Cross-Sectional Study in a Middle Eastern Country
Malik Sallam,Kholoud Al-Mahzoum,Ala’a B. Al-Tammemi,Mohammed A. AlKurtas,Fatemeh Mirzaei,Nariman Kareem,Hala Al-Naimat,Laila Jardaneh,Laith Al-Majali,Akram AlHadidi,Khaled Al-Salahat,Eyad Al-Ajlouni,Nadin Mohammad AlHadidi,Faris G. Bakri,Harapan Harapan,Azmi Mahafzah +15 more
TL;DR: The endorsement of conspiracy beliefs about virus emergence was associated with lower H MPX knowledge, the belief in the role of male homosexuals in HMPX spread, and with lower diagnosis and management confidence levels.
References
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Journal ArticleDOI
Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022.
John Thornhill,Sapha Barkati,Sharon Walmsley,Juergen K. Rockstroh,Andrea Antinori,Luke B Harrison,Romain Palich,Achyuta V Nori,I. Reeves,Maximillian S. Habibi,Vanessa Apea,Christoph Boesecke,Linos Vandekerckhove,M. V. Yakubovsky,Elena Sendagorta,José L. Blanco,Eric Florence,Davide Moschese,Fernando Maltez,Abraham Goorhuis,Valérie Pourcher,Pascal Migaud,Sebastian Noe,Claire Pintado,Fabrizio Maggi,Ann-Brit Eg Hansen,Christian Hoffmann,Jezer I Lezama,Cristina Mussini,Anna Maria Cattelan,Keletso Makofane,Darrell H. S. Tan,Silvia Nozza,J. Nemeth,Marina B Klein,Chloe Orkin +35 more
TL;DR: The simultaneous identification of cases outside areas where monkeypox has traditionally been endemic highlights the need for rapid identification and diagnosis of cases to contain further community spread.
Journal ArticleDOI
Estimating per-act HIV transmission risk: a systematic review.
TL;DR: The risk of HIV acquisition varied widely, and the estimates for receptive anal intercourse increased compared with previous estimates, while the risk associated with sexual intercourse was reduced most substantially by the combined use of condoms and antiretroviral treatment of HIV-infected partners.
Journal ArticleDOI
Clinical features and management of human monkeypox: a retrospective observational study in the UK
Hugh Adler,Susan M Gould,Paul Hine,Luke B Snell,Waison Wong,Catherine F Houlihan,Jane Osborne,Tommy Rampling,Mike B.J. Beadsworth,Christopher J A Duncan,Jake Dunning,Tom Fletcher,Ewan Hunter,Michael R. Jacobs,Saye Khoo,William Newsholme,David Porter,R Jefferson Porter,L. Ratcliffe,Matthias Schmid,Malcolm G Semple,Anne Tunbridge,Tom Wingfield,Nicholas Price,Michael Abouyannis,Asma Al-Balushi,Stephen Aston,Robert Ball,Nicholas J. Beeching,Tom Blanchard,Ffion Carlin,Geraint Davies,Angela Gillespie,Scott Rory Hicks,Marie-Claire Hoyle,C. Ilozue,L. Mair,Suzanne Marshall,Ann Neary,Emmanuel Nsutebu,Samantha Parker,Hannah Ryan,Lance Turtle,Christie A. Smith,Jon Jurriaan van Aartsen,N. Walker,Stephen D. Woolley,A. Chawla,Ian J Hart,Anna Smielewska,Elizabeth Joekes,Cathryn Benson,Cheryl Brindley,Urmi Das,Chin Kien Eyton-Chong,Claire Gnanalingham,Claire Halfhide,Beatriz Larru,Sarah Mayell,Joanna McBride,Claire Oliver,Princy Gupta and Satya Paul,Andrew Riordan,L. S. Sridhar,Megan Storey,Audrey Abdul,Jennifer Abrahamsen,Breda Athan,Sanjay Bhagani,Colin S Brown,Oliver L. Carpenter,Ian Cropley,Kerrie Frost,Susan Hopkins,Jessie Briggs Joyce,Lucy E Lamb,Adrian Lyons,Tabitha Mahungu,Stephen Mepham,Edina Mukwaira,Alison Rodger,Caroline Taylor,Simon Warren,Alan Williams,Debbie Levitt,D.O. Allen,Jill Dixon,Adam Evans,Paul McNicholas,Brendan A I Payne,David Price,Ulrich Schwab,Allison Sykes,Yusri Taha,Margaret May Ward,Marieke Emonts,Stephen Owens,A Botgros,Sam Douthwaite,Anna Goodman,Akish Luintel,Eithne MacMahon,G. Nebbia,Geraldine O’Hara,Joseph Parsons,Ashwin Sen,Daniel R Stevenson,Tadgh Sullivan,Usman Taj,Claire van Nipsen tot Pannerden,Helen Winslow,Ewa Zatyka,Ekene Alozie-Otuka,C. Beviz,Yusupha Ceesay,Latchmin Gargee,M. Kabia,H. Mitchell,Shona Perkins,Mingaile Sasson,Kamal Sehmbey,Federico Tabios,Neil Wigglesworth,Emma Aarons,Tim Brooks,Matthew Dryden,Jenna Furneaux,Barry C. Gibney,Jennifer L. Small,Elizabeth C Truelove,Clare Warrell,Richard W. Firth,Gemma Louise Hobson,Christopher Johnson,A. Dewynter,S.G. Nixon,Oliver Spence,Joachim Jakob Bugert,Dennis E. Hruby +138 more
TL;DR: The longitudinal clinical course of monkeypox in a high-income setting, coupled with viral dynamics, and any adverse events related to novel antiviral therapies are described, to highlight the urgent need for prospective studies of antivirals for this disease.
Journal ArticleDOI
Outbreak of human monkeypox in Nigeria in 2017-18: a clinical and epidemiological report.
Adesola Yinka-Ogunleye,Olusola Aruna,Mahmood Dalhat,Dimie Ogoina,Andrea M. McCollum,Yahyah Disu,Ibrahim Mamadu,Afolabi Akinpelu,Adama Ahmad,Joel Burga,Adolphe Ndoreraho,Edouard Nkunzimana,Lamin Manneh,Amina Mohammed,Olawunmi Adeoye,Daniel Tom-Aba,Bernard C. Silenou,Oladipupo Ipadeola,Muhammad H A Saleh,Ayodele Adeyemo,Ifeoma Nwadiutor,Neni Aworabhi,Patience Uke,Doris John,Paul Wakama,Mary G. Reynolds,Matthew R. Mauldin,Jeffrey B. Doty,Kimberly Wilkins,Joy Musa,Asheena Khalakdina,Adebayo Adedeji,Nwando,Olubunmi Ojo,Gérard Krause,Chikwe Ihekweazu,Anna Mandra,Whitni Davidson,Victoria A. Olson,Yu Li,Kay Radford,Hui Zhao,Michael B. Townsend,Jillybeth Burgado,Panayampalli Subbian Satheshkumar +44 more
TL;DR: The results suggest endemicity of monkeypox virus in Nigeria, with some evidence of human-to-human transmission, and further studies are necessary to explore animal reservoirs and risk factors for transmission of the virus.
Journal ArticleDOI
Clinical Characteristics of Human Monkeypox, and Risk Factors for Severe Disease
Gregory D. Huhn,Audrey M. Bauer,Krista L. Yorita,Mary Beth Graham,James J. Sejvar,Anna Likos,Inger K. Damon,Mary G. Reynolds,Matthew J. Kuehnert +8 more
TL;DR: In this article, a confirmed case of monkeypox was found in 34 patients, 5 (15%) were defined as severely ill, and 9 (26%) were hospitalized for 148 hours; no patients died.