Journal ArticleDOI
Comparisons Between Mammalian and Artificial Olfaction Based on Arrays of Carbon Black—Polymer Composite Vapor Detectors
TLDR
In this article, a man-made implementation of an olfactory system is presented, in which an analyte elicits a response from many receptors and each receptor responds to a variety of analytes.Abstract:
Arrays of broadly cross-reactive vapor sensors provide a man-made implementation of an olfactory system, in which an analyte elicits a response from many receptors and each receptor responds to a variety of analytes. Pattern recognition methods are then used to detect analytes based on the collective response of the sensor array. With the use of this architecture, arrays of chemically sensitive resistors made from composites of conductors and insulating organic polymers have been shown to robustly classify, identify, and quantify a diverse collection of organic vapors, even though no individual sensor responds selectively to a particular analyte. The properties and functioning of these arrays are inspired by advances in the understanding of biological olfaction, and in turn, evaluation of the performance of the man-made array provides suggestions regarding some of the fundamental odor detection principles of the mammalian olfactory system.read more
Citations
More filters
Journal ArticleDOI
An electronic nose in the discrimination of patients with asthma and controls
Silvano Dragonieri,Robert Schot,Bart Mertens,Saskia le Cessie,S A Gauw,Antonio Spanevello,Onofrio Resta,Nico Willard,Teunis J. Vink,Klaus F. Rabe,Elisabeth H. Bel,Peter J. Sterk,Peter J. Sterk +12 more
TL;DR: These findings warrant validation of electronic noses in diagnosing newly presented patients with asthma, and patients with mild and severe asthma could be less well discriminated.
Journal ArticleDOI
An electronic nose in the discrimination of patients with non-small cell lung cancer and COPD.
Silvano Dragonieri,Silvano Dragonieri,Jouke T. Annema,Robert Schot,Marc P. van der Schee,Marc P. van der Schee,Antonio Spanevello,Pierluigi Carratù,Onofrio Resta,Klaus F. Rabe,Peter J. Sterk,Peter J. Sterk +11 more
TL;DR: VOC-patterns of exhaled breath discriminates patients with lung cancer from COPD patients as well as healthy controls, and the electronic nose may qualify as a non-invasive diagnostic tool for lung cancer in the future.
Journal ArticleDOI
Human exhaled breath analysis.
TL;DR: Examination of exhaled breath has the potential to change the existing routine approaches in human medicine and the rapidly developing new analytical and computer technologies along with novel, unorthodox ideas are prerequisites for future advances in this field.
Journal ArticleDOI
An electronic nose distinguishes exhaled breath of patients with Malignant Pleural Mesothelioma from controls.
Silvano Dragonieri,Silvano Dragonieri,Marc P. van der Schee,T Massaro,Schiavulli N,Paul Brinkman,Armando Pinca,Pierluigi Carratù,Antonio Spanevello,Onofrio Resta,Marina Musti,Peter J. Sterk +11 more
TL;DR: Molecular pattern recognition of exhaled breath can correctly distinguish patients with MPM from subjects with similar occupational asbestos exposure without MPM and from healthy controls, which suggests that breathprints obtained by electronic nose have diagnostic potential for MPM.
Journal ArticleDOI
Electronic Nose Technology for Detection of Invasive Pulmonary Aspergillosis in Prolonged Chemotherapy-Induced Neutropenia: a Proof-of-Principle Study
Koen de Heer,Marc P. van der Schee,Koos Zwinderman,Inge A.H. van den Berk,Caroline E. Visser,Rien van Oers,Peter J. Sterk +6 more
TL;DR: Preliminary data indicate that PCIN patients with IA have a distinct exhaled VOC profile that can be detected with eNose technology, and the diagnostic accuracy of the eN Nose for invasive aspergillosis warrants validation.
References
More filters
Journal ArticleDOI
Comparisons between Mammalian and Artificial Olfaction Based on Arrays of Carbon Black−Polymer Composite Vapor Detectors
TL;DR: Evaluation of the performance of the man-made array provides suggestions regarding some of the fundamental odor detection principles of the mammalian olfactory system.
Related Papers (5)
Comparisons between Mammalian and Artificial Olfaction Based on Arrays of Carbon Black−Polymer Composite Vapor Detectors
Differential receptor arrays and assays for solution-based molecular recognition
Aaron T. Wright,Eric V. Anslyn +1 more
Combining Two Selection Principles: Sensor Arrays Based on Both Biomimetic Recognition and Chemometrics.
Wim Cuypers,Peter A. Lieberzeit +1 more