Journal ArticleDOI
Computational fluid dynamics (CFD) software tools for microfluidic applications – A case study
Thomas Glatzel,Christian Litterst,Claudio Cupelli,Timo Lindemann,C Moosmann,Remigius Niekrawietz,Wolfgang Streule,Roland Zengerle,Peter Koltay +8 more
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TLDR
An exemplary study of the performance of commercial computational fluid dynamic (CFD) software programs when applied as engineering tool for microfluidic applications and the capability of the software programs to deal with free surface flows including surface tension and flow patterns of two fluids is studied.About:
This article is published in Computers & Fluids.The article was published on 2008-03-01. It has received 143 citations till now. The article focuses on the topics: Computational fluid dynamics & Software.read more
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Numerical modeling of multiphase flows in microfluidics and micro process engineering: a review of methods and applications
TL;DR: A comprehensive review of numerical methods and models for interface resolving simulations of multiphase flows in microfluidics and micro process engineering is presented in this paper, where three common approaches in the sharp interface limit, namely the volume-of-fluid method with interface reconstruction, the level set method and the front tracking method, as well as methods with finite interface thickness such as color function based methods and the phase-field method are discussed.
Journal ArticleDOI
Microfluidic DNA microarray analysis: a review.
Lin Wang,Paul C. H. Li +1 more
TL;DR: The recent microfluidic hybridization method shows the advantages of less sample usage and reduced incubation time and the high surface-to-volume ratio in microchannels of nanolitre volume greatly enhanced the sensitivity as obtained with the bulk solution method.
Journal ArticleDOI
Numerical and experimental studies of mixing characteristics in a T-junction microchannel using residence-time distribution
John T. Adeosun,Adeniyi Lawal +1 more
TL;DR: In this article, the mixing behavior in laminar flow in microchannels is investigated using numerical and experimental approaches using the concept of residence-time distribution (RTD) to indirectly characterize flow and mixing in a T-junction microchannel chosen as a model microchannel mixer/reactor.
Journal ArticleDOI
A review on numerical studies of slug flow hydrodynamics and heat transfer in microtubes and microchannels
TL;DR: Numerical studies on the hydrodynamic and heat transfer characteristics of two-phase flows in small tubes and channels are reviewed in this paper, where the authors highlight the research gaps and suggestions for the future numerical simulations.
Journal ArticleDOI
Integration of methanol steam reforming and combustion in a microchannel reactor for H2 production: A CFD simulation study
Gurutze Arzamendi,P.M. Diéguez,Mario Montes,Miguel Ángel Centeno,José Antonio Odriozola,Luis M. Gandía +5 more
TL;DR: In this paper, a computational fluid dynamics (CFD) study of the thermal integration of the steam reforming of methanol and combustion in a catalytic micro-channel reactor is presented.
References
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Journal ArticleDOI
Volume of fluid (VOF) method for the dynamics of free boundaries
C.W Hirt,B. D. Nichols +1 more
TL;DR: In this paper, the concept of a fractional volume of fluid (VOF) has been used to approximate free boundaries in finite-difference numerical simulations, which is shown to be more flexible and efficient than other methods for treating complicated free boundary configurations.
Journal ArticleDOI
A continuum method for modeling surface tension
TL;DR: In this paper, a force density proportional to the surface curvature of constant color is defined at each point in the transition region; this force-density is normalized in such a way that the conventional description of surface tension on an interface is recovered when the ratio of local transition-reion thickness to local curvature radius approaches zero.
Book
An Introduction to Computational Fluid Dynamics: The Finite Volume Method
TL;DR: This chapter discusses the development of the Finite Volume Method for Diffusion Problems, a method for solving pressure-Velocity Coupling in Steady Flows problems, and its applications.
Book
Computational methods for fluid dynamics
Joel H. Ferziger,Milovan Perić +1 more
TL;DR: This text develops and applies the techniques used to solve problems in fluid mechanics on computers and describes in detail those most often used in practice, including advanced techniques in computational fluid dynamics.
Journal ArticleDOI
A level set approach for computing solutions to incompressible two-phase flow
TL;DR: A level set method for capturing the interface between two fluids is combined with a variable density projection method to allow for computation of two-phase flow where the interface can merge/break and the flow can have a high Reynolds number.