Journal ArticleDOI
CONCENTRATIONS OF THE PROSTACYCLIN METABOLITE, 6–KETO–PROSTAGLANDIN F1α, IN AMNIOTIC FLUID DURING LATE PREGNANCY AND LABOUR.
TLDR
It is suggested that prostacyclin may have a functional role in the mechanism of parturition in man as measured in amniotic fluid obtained during late pregnancy and labour.About:
This article is published in British Journal of Obstetrics and Gynaecology.The article was published on 1979-05-01. It has received 39 citations till now. The article focuses on the topics: Amniotic fluid & Prostacyclin.read more
Citations
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Journal ArticleDOI
Prostacyclin and thromboxane in gynecology and obstetrics.
TL;DR: The gynecologic and obstetric implications of the smooth muscle-relaxing, antiaggregatory prostacyclin and its endogenous antagonist, thromboxane A2, are reviewed and it is possible to prevent and/or treat hypertensive pregnancy complications in the future.
Book ChapterDOI
Initiation of parturition.
TL;DR: The pendulum swung decisively away from maternal control towards fetal control and the fetal endocrine system became the focus of attention of most investigators.
Journal ArticleDOI
Prostaglandins and the myometrium and cervix
Frank Hertelendy,Tamas Zakar +1 more
TL;DR: The premier role of progesterone in pregnancy maintenance and parturition is juxtaposed with the proposed "fine-tuning", modulatory role of prostaglandins and the above listed factors in the regulation of parturitions.
Journal ArticleDOI
Mobilization of arachidonic acid from specific glycerophospholipids of human fetal membranes during early labor.
TL;DR: During early labor, there is a net release of arachidonic acid specifically from diacyl phosphatidylethanolamine andosphatidylinositol of amnion and chorion laeve, which can be accounted for by enzymatic activities that are relatively specific for the release ofArachid sonic acid from these two glycerophospholipids.
References
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Journal ArticleDOI
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation.
TL;DR: A balance between formation of anti- and pro-aggregatory substances by enzymes could also contribute to the maintenance of the integrity of vascular endothelium and explain the mechanism of formation of intra-arterial thrombi in certain physiopathological conditions.
Journal ArticleDOI
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.
TL;DR: Evidence is presented that the more unstable and major component of rabbit aorta contracting substance (RCS) formed in platelets and guinea pig lung is also thromboxane A2.
Journal ArticleDOI
Radioimmunoassay of Prostaglandins Fα, E1 and E2 in Human Plasma
TL;DR: Antibodies against prostaglandins were obtained in rabbits immunized with respectively PG F2α, PG E1 and PG E2 conjugated to bovine serum albumin by carbodiimide.
Journal ArticleDOI
Prostaglandin content of amniotic fluid during pregnancy and labour
Sultan M. M. Karim,Jean Devlin +1 more
TL;DR: A total of 38 individual specimens of amniotic fluid obtained at various stages of pregnancy and during labour were investigated for presence of prostaglandins, finding that they are formed in the cells of the decidua.
Related Papers (5)
E prostaglandins in amniotic fluid during late pregnancy and labour.
Primary prostaglandins in amniotic fluid in pregnancy and spontaneous labor
F. Dray,R. Frydman +1 more