Journal ArticleDOI
Configuration and conformation of the products of reaction of 3,4-di-O-acetyl-2-deoxy-2-nitroso-β-d-arabinopyranosyl chloride with pyrazole
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TLDR
In this paper, the configuration and conformation of pyrazole were established on the basis of 1H-n.m., polarimetric, and crystallographic data, the configuration of which was established based on 1H n.m.About:
This article is published in Carbohydrate Research.The article was published on 1988-02-01. It has received 16 citations till now. The article focuses on the topics: Pyrazole & Nitroso.read more
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New Trends in Synthesis of Pyrazole Nucleosides as New Antimetabolites
TL;DR: Recent synthetic approaches to pyrazole nucleosides preparation, chemical properties, biological activities, and structure-activity relationships are described, with emphasis to selected drugs or drug candidates.
Journal ArticleDOI
Alternative Syntheses of L-(-)-Oleandrose from L-Rhamnose1 Preparation of Glycals
TL;DR: In this paper, an improved generalized Fischer-Zach reaction was used to convert L-Rhamnal (2) to L-(-)-oleandrose (1) by stannylene mediated selective methylation and effective hydration.
Journal ArticleDOI
New synthesis of L-FMAU from L-arabinose.
TL;DR: A new synthesis of 2′-deoxy-2′-fluoro-5-methyl-β-L-arabinofuranosyl uracil (13, L-FMAU) was achieved in 10 steps from L-arbenose.
Journal ArticleDOI
Chlorodifluoromethyl-substituted monosaccharide derivatives--radical activation of the carbon-chlorine-bond.
TL;DR: UV-initiated allylations are reported for reactions of (2-deoxy-3,4-di-O-pivaloyl-beta-D-threo-pentopyranosyl)-chlorodifluoromethane, and hydrodechlorinated or alkylated at the CF(2)Cl-group using tin reagents under radical reaction conditions.
Patent
Process for the preparation of 2'-halo-beta-l-arabinofuranosyl nucleosides
TL;DR: In this article, the authors presented a process for the preparation of 2'-deoxy-2'-halo-β-L-arabinofuranosyl nucleosides, and in particular, 2'deoxy -2'-fluoro-β -L-Arabinofuranousyl thymine (L-FMAU), from L -arabinose, which is commercially available and less expensive than L-ribose or L-xylose, in ten steps.
References
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International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Journal ArticleDOI
General definition of ring puckering coordinates
Dieter Cremer,John A. Pople +1 more
TL;DR: In this article, a unique mean plane is defined for a general monocyclic puckered ring, which is described by amplitude and phase coordinates which are generalizations of those introduced for cyclopentane by Kilpatrick, Pitzer, and Spitzer.
Journal ArticleDOI
Application of ab initio molecular orbital calculations to the structural moieties of carbohydrates. 3
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A survey of O-H⋯O hydrogen bond geometries determined by neutron diffraction
TL;DR: An analysis of the geometries of one hundred O-H⋯O hydrogen bonds observed by neutron diffraction in 24 crystal structures showed the following results as discussed by the authors : Twenty-five of the hydrogen bonds can be described as bifurcated, indicating that this form of association is more common than previously supposed.