Journal ArticleDOI
Control of self-assembling oligopeptide matrix formation through systematic variation of amino acid sequence.
Michael R. Caplan,Elissa M. Schwartzfarb,Shuguang Zhang,Roger D. Kamm,Douglas A. Lauffenburger +4 more
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TLDR
A class of oligopeptides that can self-assemble in salt solutions to form three-dimensional matrices is investigated, and it is found that increasing side-chain hydrophobicity decreases the critical salt concentration in accord with previous validation of DLVO theory.About:
This article is published in Biomaterials.The article was published on 2002-01-01. It has received 282 citations till now.read more
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Fabrication of novel biomaterials through molecular self-assembly.
TL;DR: Two complementary strategies can be used in the fabrication of molecular biomaterials as discussed by the authors : chemical complementarity and structural compatibility, both of which confer the weak and noncovalent interactions that bind building blocks together during self-assembly.
PatentDOI
Self-assembly and mineralization of peptide-amphiphile nanofibers
TL;DR: In this paper, pH-induced self-assembly of a peptide-amphiphile was used to make a nanostructured fibrous scaffold reminiscent of extracellular matrix.
Journal ArticleDOI
BIOMATERIALS: Where We Have Been and Where We Are Going
TL;DR: This new generation of biomaterials includes surface modification of materials to overcome nonspecific protein adsorption in vivo, precision immobilization of signaling groups on surfaces, and design of sophisticated three-dimensional architectures to produce well-defined patterns for diagnostics.
Journal ArticleDOI
Designing peptide based nanomaterials
Rein V. Ulijn,Andrew M. Smith +1 more
TL;DR: This tutorial review looks at the design rules that allow peptides to be exploited as building blocks for the assembly of nanomaterials and the applications of designed self-assembly peptide systems in biotechnology, technology and science.
Journal ArticleDOI
Responsive Hydrogels from the Intramolecular Folding and Self-Assembly of a Designed Peptide
Joel P. Schneider,Darrin J. Pochan,Bulent Ozbas,Karthikan Rajagopal,Lisa Pakstis,Juliana Kretsinger +5 more
TL;DR: Characterization of the gelation process, from the molecular level up through the macroscopic properties of the material, suggests that by linking the intramolecular folding of small designed peptides to their ability to self-assemble, responsive materials can be prepared.
References
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Book
Proteins: Structures and Molecular Properties
TL;DR: This paper discusses the physical properties of polypeptides, the structure of which has been determined Crystallographically to High Resolution and its role in the biosynthesis of Proteins.
Book
Principles of colloid and surface chemistry
Paul C. Hiemenz,Raj Rajagopalan +1 more
TL;DR: Colloid and surface chemistry - scope and variables sedimentation and diffusion and their equilibrium solution thermodynamics - osmotic and Donnan equilibria the rheology of dispersions static and dynamic light scattering and other radiation scattering surface tension and contact angle - application to pure substances adsorption from solution and monolayer formation colloidal structures in surfactant solutions - association colloids adsorction at gas-solid interfaces van der Waals forces the electrical double layer and double-layer interactions electrophoresis and other electrokinetic phenomena electrostatic and polymer-induced
Book
The Hydrophobic Effect: Formation of Micelles and Biological Membranes
TL;DR: In this article, the authors discuss the properties of water molecules and their relationship with common soluble proteins, such as membrane proteins and membrane membrane proteins, as well as the effect of temperature on their properties.
Journal ArticleDOI
Theory of the Stability of Lyophobic Colloids
TL;DR: Theory of the Stability of Lyophobic Colloids The Interaction of Sol Particles having an Electric Double Layer and the nature of the electrical double layer which exists around them in salt solutions is discovered.