Journal ArticleDOI
Control of Tachyarrhythmias Associated with Wolff-Parkinson-White Syndrome by Amiodarone Hydrochloride
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TLDR
Amiodarone hydrochloride proved to be highly effective in preventing and treating arrhythias of the Wolff-Parkinson-White (WPW) syndrome in 11 patients with WPW conduction and recurrent tachyarrhythmias.Abstract:
Amiodarone hydrochloride proved to be highly effective in preventing and treating arrhythmias of the Wolff-Parkinson-White (WPW) syndrome in 11 patients with WPW conduction and recurrent tachyarrhythmias Paroxysmal supraventricular tachycardia (six patients), atrial fibrillation (four patients) and atrial flutter (one patient) were the most significant arrhythmias In most patients the arrhythmia was seriously disabling because of the extremely rapid ventricular rate, adverse hemodynamic consequences and frequent recurrence and long duration of the episodes Other known antiarrhythmic agents were ineffective In all 11 patients amiodarone, in doses of 300 to 600 mg daily, totally, easily and safety controlled the arrhythmias for periods of 2 to 8 months The drug was fully effective after an average of 7 days of treatment Tolerance to amiodarone was excellent The occurrence of corneal microdeposits of the drug was the only Important undesirable effect, but subjective ocular disturbances were not noted The microdeposits are reversible, and can be avoided by discontinuing the drug for 7 days every 1 to 2 months Amiodarone apparently causes a significant prolongation of refractoriness in the normal (A-V node and His-Purkinje system) as well as in the anomalous pathway, thus creating favorable conditions for prevention and Interruption of any reentry mechanism requiring participation of both pathwaysread more
Citations
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Journal ArticleDOI
ACC/AHA/ESC Guidelines for the Management of Patients with Supraventricular Arrhythmias - Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients with Supraventricular Arrhythmias)
Carina Blomström-Lundqvist,Melvin M. Scheinman,Etienne Aliot,Joseph S. Alpert,Hugh Calkins,A. John Camm,W. Barton Campbell,David E. Haines,Karl H. Kuck,Bruce B. Lerman,D. Douglas Miller,Charlie Willard Shaeffer,William G. Stevenson,Gordon F. Tomaselli,Elliott M. Antman,Sidney C. Smith,David P. Faxon,Valentin Fuster,Raymond J. Gibbons,Gabriel Gregoratos,Loren F. Hiratzka,Sharon A. Hunt,Alice K. Jacobs,Richard O. Russell,Silvia G. Priori,Jean Jacques Blanc,A Budaj,Enrique Fernandez Burgos,Martin R. Cowie,Jaap W. Deckers,Maria Angeles Alonso Garcia,Werner Klein,John Lekakis,Bertil Lindahl,Gianfranco Mazzotta,João Morais,Ali Oto,Otto A. Smiseth,Hans Joachim Trappe +38 more
TL;DR: New guidelines for the management of patients with supraventricular arrhythmias are introduced and recommended for use in combination with standard clinical practice.
Journal ArticleDOI
The preexcitation syndromes.
TL;DR: Surgery offers a feasible therapeutic alternative for patients with life-threatening or disabling arrhythmias but demands a team equipped to perform precise preoperative and intraoperative mapping studies to define the type and location of underlying anatomic substrates.
Journal ArticleDOI
A Classification of Antiarrhythmic Actions Reassessed After a Decade of New Drugs
TL;DR: All but one of the new antiarrhythmic drugs introduced since 1972 have turned out to possess one or more of the four classes of action originally described, and recent research suggests that inhibition of slow inward current may lead, as a secondary consequence of lowered [Ca]i, to improved cell-to-cell conduction.
ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmiasM — executive summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias)
Joseph S. Alpert,Elliott M. Antman,Sidney C. Smith,David P. Faxon,Valentin Fuster,Raymond J. Gibbons,Gabriel Gregoratos,Loren F. Hiratzka,Sharon A. Hunt,Alice K. Jacobs,Richard O. Russell +10 more
TL;DR: Blomstrom-Lundqvist et al. as discussed by the authors proposed the ESC guidelines for the management of patients with supraventricular arrhythmias, which are based on the guidelines of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Journal ArticleDOI
ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias∗—executive summary: a report of the American college of cardiology/American heart association task force on practice guidelines and the European society of cardiology committee for practice guidelines (writing committee to develop guidelines for the management of patients with supraventricular arrhythmias) Developed in Collaboration with NASPE-Heart Rhythm Society☆
TL;DR: In this paper, the authors present a set of guidelines for the diagnosis and management of supraventricular arrhythmias, which are intended to assist physicians in clinical decision-making by describing a range of generally acceptable approaches.
References
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Journal ArticleDOI
The effect of amiodarone, a new anti‐anginal drug, on cardiac muscle
TL;DR: It was concluded that amiodarone had effects on cardiac action potentials similar to those which occur after thyroidectomy.
Journal ArticleDOI
The Role of Premature Beats in the Initiation and the Termination of Supraventricular Tachycardia in the Wolff-Parkinson-White Syndrome
TL;DR: In four patients with WPW syndrome atrial and ventricular premature beats were induced and the changes in form of the ventricular and atrial complexes were studied, results suggest that a circus movement involving the atria, the normal atrioventricular conduction system and the Kent bundle is present.
Journal ArticleDOI
Successful Surgical Interruption of the Bundle of Kent in a Patient with Wolff-Parkinson-White Syndrome
Frederick R. Cobb,Sarah D. Blumenschein,Will C. Sealy,John P. Boineau,Galen S. Wagner,Andrew G. Wallace +5 more
TL;DR: Surgical transection of the atrioventricular junction at that point abolished the electrocardiographic features of WPW and the recurrent tachycardia, and five months after surgery the signs and symptoms of congestive heart failure have subsided, and the patient has returned to work.
Journal ArticleDOI
Ventricular fibrillation. A possible mechanism of sudden death in patients and Wolff-Parkinson-White syndrome.
TL;DR: The control of recurrent ventricular fibrillation with large doses of digitalis and other antiarrhythmic drugs, including propranolol, lidocaine, procainamide, and quinidine, is discussed.
Journal ArticleDOI
Epicardial Excitation of the Ventricles in a Patient with Wolff-Parkinson-White Syndrome (Type B)
D. Durrer,J. P. Roos +1 more
TL;DR: Epicardial excitation was explored by means of an exploring electrode during operation on a patient with a large atrial septal defect of the secundum type, whose ECG indicated a Wolff-Parkinson-White syndrome of type B.