Journal ArticleDOI
Conventional and Microwave‐Assisted Synthesis and Biological Activity Study of Novel Heterocycles Containing Pyran Moiety
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This article is published in Journal of Heterocyclic Chemistry.The article was published on 2019-07-01. It has received 16 citations till now. The article focuses on the topics: Pyran & Moiety.read more
Citations
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Journal ArticleDOI
Conventional and microwave reactions of 1,3‐diaryl‐5,4‐enaminonitrile‐pyrazole derivative with expected antimicrobial and anticancer activities
Kurls E. Anwer,Galal H. Sayed +1 more
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MCM-41@Schiff base-Co(OAc)2 as an efficient catalyst for the synthesis of pyran derivatives
TL;DR: In this article, the CoSchiff base complex was characterized using various spectroscopic techniques to obtain the structural and functional features of the mesoporous-complex catalyst and a plausible reaction mechanism was proposed.
Journal ArticleDOI
Design, Green Synthesis and Tailoring of Vitamin E TPGS Augmented Niosomal Nano-Carrier of Pyrazolopyrimidines as Potential Anti-Liver and Breast Cancer Agents with Accentuated Oral Bioavailability
TL;DR: The present study suggests that pyrazolopyrimidine derivatives are a novel class of anti-cancer drug candidates to inhibit VEGF-VEGFR function.
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Synthesis and anticancer assessment of some new 2-amino-3-cyanopyridine derivatives
TL;DR: The 2-Aminonicotinonitrile derivative was reacted with different bi-functional reagents such as formamide, thiourea, acetic anhydride, and phthalic anhydide under optimized conditions to give pyri...
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Conventional and microwave-assisted synthesis, anticancer evaluation, 99mTc-coupling and In-vivo study of some novel pyrazolone derivatives.
TL;DR: In this paper , pyrazolone derivatives were successfully synthesized by both microwave assisted and conventional techniques, and compound 3 (3-(3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)-3-oxopropanehydrazide) displayed remarkable anti-cancer activity.
References
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Screening of hepatoprotective plant components using a HepG2 cell cytotoxicity assay
TL;DR: A screening assay has been developed based on protection of human liver‐derived HepG2 cells against toxic damage that is effective in quantifying the active components of plants with hepatoprotective properties during fractionation and purification.
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Pyranocoumarins: A new class of anti-hyperglycemic and anti-dyslipidemic agents
Atul Kumar,Ram Awatar Maurya,Siddharth Sharma,Pervez Ahmad,Amar B. Singh,Gitika Bhatia,Arvind K. Srivastava +6 more
TL;DR: In vitro anti-hyperglycemic activity evaluation exhibited that compounds 8a and 8b are potential PTP-1B inhibitors thereby revealing their possible mechanism of anti-diabetic action.
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Surface cleaning under combined microwave and ultrasound irradiation: flash synthesis of 4H-pyrano[2,3-c]pyrazoles in aqueous media
TL;DR: In this paper, a clean, rapid and energy-efficient approach to solidaqueous heterogeneous reactions was developed utilizing the synergistic effect of microwave and ultrasound irradiation, and the acceleration in reaction rates might be explained by the removal of a passivation coating on the substrate particles and the resultant enhancement in mass and heat transfer.
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Green approach towards the facile synthesis of dihydropyrano(c)chromene and pyrano[2,3-d]pyrimidine derivatives and their biological evaluation
TL;DR: A simple and efficient one-pot synthesis of heteroaryl-substituted dihydropyrano(c)chromenes and pyrano[2,3-d]pyrimidines has been developed as discussed by the authors.
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Chimpanzees recognize their own delayed self-image
TL;DR: These findings suggest that chimpanzees, like human children at the age of 4 years and more, can comprehend temporal dissociation in their concept of self.