Journal ArticleDOI
Coronary heart disease in the Western collaborative group study. A follow-up experience of two years.
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For example, this article found that the type A behavior pattern was strongly associated with the CHD incidence, and this association could not be explained by association of behavior pattern with any single predictive risk factor or with any combination of them.Abstract:
Clinical coronary heart disease (CHD) occurred in 257 subjects during eight to nine years of follow-up (average, 8 1/2 years) in a prospective study of 39- to 59-year-old employed men. Incidence of CHD was significantly associated with parental CHD history, reported diabetes, schooling, smoking habits, overt behavior pattern, blood pressure, and serum levels of cholesterol, triglyceride, and β-lipoproteins. The type A behavior pattern was strongly related to the CHD incidence, and this association could not be explained by association of behavior pattern with any single predictive risk factor or with any combination of them. ( JAMA 233:872-877, 1975)read more
Citations
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Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy.
TL;DR: Suggestions to improve the assessment of behavioral interventions include more complete delineation of the physiological mechanisms by which such interventions might work; increased use of new, more convenient "alternative" end points for behavioral intervention trials; development of specifically targeted behavioral interventions (based on profiling of patient factors); and evaluation of previously developed models of predicting behavioral change.
Journal ArticleDOI
Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies.
TL;DR: Based on combined data from prospective studies, triglyceride is a risk factor for cardiovascular disease for both men and women in the general population, independent of HDL cholesterol.
Journal ArticleDOI
Triglycerides and the Risk of Coronary Heart Disease 10 158 Incident Cases Among 262 525 Participants in 29 Western Prospective Studies
Nadeem Sarwar,John Danesh,Gudny Eiriksdottir,Gunnar Sigurdsson,Nicholas J. Wareham,Sheila Bingham,S. Matthijs Boekholdt,Kay-Tee Khaw,Vilmundur Gudnason +8 more
TL;DR: Available prospective studies in Western populations consistently indicate moderate and highly significant associations between triglyceride values and coronary heart disease risk, however, further studies are needed to help assess the nature of any independent associations.
Journal ArticleDOI
Occupational sources of stress: a review of the literature relating to coronary heart disease and mental ill health
Cary L. Cooper,Judi Marshall +1 more
TL;DR: Coronary heart disease and mental ill health together, therefore, represent a serious cost for industry both in human and financial terms.
Journal ArticleDOI
Depression as a predictor for coronary heart disease. a review and meta-analysis
TL;DR: It is concluded that depression predicts the development of CHD in initially healthy people and the stronger effect size for clinical depression compared to depressive mood points out that there might be a dose-response relationship between depression and CHD.
References
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Journal ArticleDOI
Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease
Nathan Mantel,William Haenszel +1 more
TL;DR: In this paper, the role and limitations of retrospective investigations of factors possibly associated with the occurrence of a disease are discussed and their relationship to forward-type studies emphasized, and examples of situations in which misleading associations could arise through the use of inappropriate control groups are presented.
Journal ArticleDOI
Micromethod for the direct determination of serum triglycerides.
E. Van Handel,D.B. Zilversmit +1 more
TL;DR: A microprocedure for the direct determination of triglyceride concentrations in biologic specimens is presented and depends on the quantitative removal of phosphatides from the sample and the subsequent determination of esterified glycerol.
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Association of specific overt behavior pattern with blood and cardiovascular findings: blood cholesterol level, blood clotting time, incidence of arcus senilis, and clinical coronary artery disease
Meyer Friedman,Ray H. Rosenman +1 more
TL;DR: Three groups of men, selected solely according to the behavior pattern which they habitually manifested in their work, were compared and found that this pattern per se was largely responsible for the striking differences found.
Journal ArticleDOI
A Predictive Study of Coronary Heart Disease: The Western Collaborative Group Study
Ray H. Rosenman,Meyer Friedman,Reuben Straus,Moses Wurm,Robert Kositchek,Wilfrid Hahn,Nicholas T. Werthessen +6 more
TL;DR: The profile of coronary-prone males through retrospective analysis of prospectively obtained data is defined and higher serum beta/alpha lipoprotein ratios and 80 of them had been adjudged in "blind" assessments to exhibit an overt behavior pattern previously found associated with occurrence of CHD in middle-aged men are defined.
Journal ArticleDOI
Changes in the Serum Cholesterol and Blood Clotting Time in Men Subjected to Cyclic Variation of Occupational Stress
TL;DR: Accountants were selectively chosen as a self-controlled group for studying effects of cyclic occupational stress upon serum cholesterol and blood clotting time, since their routine work schedule is interrupted by urgent tax deadlines, associated with severe occupational stress.
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Association of specific overt behavior pattern with blood and cardiovascular findings: blood cholesterol level, blood clotting time, incidence of arcus senilis, and clinical coronary artery disease
Meyer Friedman,Ray H. Rosenman +1 more