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Journal ArticleDOI

Degenerate ring transformations in heterocyclic systems

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This article is published in Journal of Heterocyclic Chemistry.The article was published on 2000-05-01. It has received 29 citations till now. The article focuses on the topics: Ring (chemistry).

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Journal ArticleDOI

Recent Developments in the Synthesis, Chemistry and Applications of the Fully Unsaturated 1,2,4-Oxadiazoles:

TL;DR: In this article, a review of the development of the fully unsaturated 1,2,4-oxadiazole nucleus is presented, covering the years 1995-2000, including solid phase methodologies, chemistry and applications.
Journal ArticleDOI

Recent Advances in Ring Transformations of Five-Membered Heterocycles and Their Fused Derivatives

TL;DR: Ring transformations of five-membered heterocycles and their benzologues for the recent 10 years are discussed and reviewed in this paper, where reaction mechanisms of the most interesting ring transformations are also discussed.
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Synthesis and ring transformation of substituted S-(1-phenylpyrrolidine-2-ones-3-yl)isothiuronium salts to substituted 2-imino-5-[2-(phenylamino)ethyl]thiazolidin-4-ones

TL;DR: Substituted S-(1-phenylpyrrolidin-2-on-3-yl)isothiuronium salts in weakly basic media undergo intramolecular recyclisation reaction in which the γ-lactam cycle is split and a thiazolidine cycle is formed as discussed by the authors.
Journal ArticleDOI

Reaction of 1-substituted 3,5-diamino-1,2,4-triazoles with β-keto esters: synthesis and new rearrangement of mesoionic 3-amino-2H-[1,2,4]triazolo-[4,3-a]pyrimidin-5-ones

TL;DR: In this article, a new type of rearrangement in the azolopyrimidine series was proposed, which is based on the reaction conditions of enaminoesters with β-keto esters.
Book ChapterDOI

1,2,4-Oxadiazoles

Karl Hemming
- 01 Dec 2008 - 
TL;DR: The uses of 1,2,4-oxadiazoles include those as agonists at muscarinic receptors, 5-hydroxytryptamine (5-HT) receptor antagonists, benzodiazepine receptor agonists, potent antagonists of the (serotonin) 5-HT1B/D receptors, muscarinates ‘superagonists’, selective inhibitors of human neutrophil elastase, and as active and selective A2B adenosine receptor antagonists.
References
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Journal ArticleDOI

Chemistry of oxazoles

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Molecular rearrangements of five-membered ring heteromonocycles

TL;DR: In this article, the authors classified molecular rearrangements of five-membered ring heterocycles into five categories based on the number of participating side-chain atoms: Dimroth rearrangement, Dimroth contraction-ring expansion (DRCE), Dimroth expansion, Cornforth, Boulton-Katritzky, and bond-switch rearranging.
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Isolation procedure and some properties of the bromoperoxidase from the seaweed Ascophyllum nodosum

TL;DR: A large-scale isolation procedure for bromoperoxidase from the brown alga Aseophyllum nodosum is described in this paper, where the enzyme showed one major band (40 kDa) after polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate.
Journal ArticleDOI

Heterocyclic rearrangements. Part X. A generalised monocyclic rearrangement

TL;DR: A new general class of rearrangements of substituted azoles (III)→(IV) has been recognized, scattered examples from the literature are collated, and further examples described.