Q1. What are the contributions in "Demographics, phenotypic health characteristics and genetic analysis of centenarians in china" ?
After a brief introduction to the background, significance and unique features of the centenarian population in China, the authors describe the Chinese Longitudinal Healthy Longevity Study ( CLHLS ), which is the world ’ s largest study of centenarians, nonagenarians, octogenarians, and compatible young-old aged 65–79. Based on the CLHLS data and other relevant studies, the authors summarize demographic and socioeconomic characteristics as well as self-reported and objectively-tested health indicators of centenarians in China, with an emphasis on gender differences and rural/urban disparities. The authors then compare five-yearage-specific trajectories of physical and cognitive functions, self-reported health, and life satisfactions from ages 65–69 to 100+, concluding that good psychological resilience and optimism are keys to the exceptional longevity enjoyed by centenarians. The authors discuss recent findings of novel loci and pathways