Journal ArticleDOI
Denervation supersensitivity to serotonin in rat forebrain : single cell studies
TLDR
In contrast to the marked supersensitivity seen after 5,7-DHT induced denervation, chronic administration of parachlorophenylalanine, a 5- HT synthesis inhibitor, failed to induce 5-HT supersensitivity.About:
This article is published in Brain Research.The article was published on 1979-12-14. It has received 108 citations till now. The article focuses on the topics: Denervation supersensitivity & Denervation.read more
Citations
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Physiopharmacological interactions between stress hormones and central serotonergic systems
TL;DR: Some mechanisms through which the sympathetic nervous system (SNS) and the hypothalamo-pituitary-adrenal (HPA) interact with central serotonergic systems are delineated, thereby conferring to these mechanisms a key role in adaptation processes.
Journal ArticleDOI
Morphine-induced activation of A10 dopamine neurons in the rat.
Katia Gysling,Rex Y. Wang +1 more
TL;DR: It appears that the MOR-induced activation of A9 DA cells does not depend on afferents from the forebrain or on projections from the DRN, suggesting a more direct action of MOR on A10 DA cells, and it is proposed that the Mor-inducedactivation of A10DA cells could be mediated indirectly by non-DA cells.
Journal ArticleDOI
Neurochemical modulation of sensory-motor reactivity: acoustic and tactile startle reflexes.
TL;DR: The present review argues that the startle reflex is particularly well suited as a model system to analyze how drugs alter stimulus reactivity and reflex excitability and that drugs or lesions that are thought to alter neurochemical transmitter systems affect acoustic and/or tactile startle.
Journal ArticleDOI
Motor effects of serotonin in the central nervous system
TL;DR: The mechanisms underlying this complex response may be mediated by descending 5-HT systems that result in motor excitation at the spinal cord level, in contrast to rostral projections to forebrain that may mediate many behaviorally inhibitory responses.
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Dopaminergic neurons in the rat ventral tegmental area. I. Identification and characterization
TL;DR: It is concluded that VTA output neurons consist of bothDA and nonDA neurons, and identified types I and II neurons in the VTA by antidromic stimulation of the NAc are DA and non-DA cells, respectively.
References
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Journal ArticleDOI
Fluorescence of Catechol Amines and Related Compounds Condensed With Formaldehyde
TL;DR: In this article, the reaction between formaldehyde and phenylalanine and phenylethylamine derivatives has been studied under mild conditions and it has been shown that the amines primarily condense with formaldehyde to 1,2,3,4-tetrahydroisoquinolines which are involved in a secondary reaction to become highly fluorescent and at the same time insoluble.
Journal Article
The isolation of nerve endings from brain: An electron microscopic study of cell fragments derived by homogenization and centrifugation
E. G. Gray,Victor P. Whittaker +1 more
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An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat
Efrain C. Azmitia,Menahem Segal +1 more
TL;DR: The differential projections from the dorsal raphe and median raphe nuclei of the midbrain were autoradiographically traced in the rat brain after 3H‐proline micro‐injections to identify six ascending fiber tracts.
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Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system.
TL;DR: In this article, the effect of L-DOPA and the dopamine receptor stimulating drug apomorphine was studied in rats after unilateral degeneration of the nigrostriatal DA system by intracerebral injection of 6-hydroxydopamine.
Journal Article
p-CHLOROPHENYLALANINE: A SPECIFIC DEPLETOR OF BRAIN SEROTONIN
B K Koe,A Weissman +1 more
TL;DR: The results suggest that p -chlorophenylalanine may effect 5HT depletion by inhibiting the biosynthesis of this monoamine, possibly by blocking tryptophan hydroxylation.