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Journal ArticleDOI

Development of a Classification System for Periodontal Diseases and Conditions

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TLDR
How the new classification for periodontal diseases and conditions presented in this volume differs from the classification system developed at the 1989 World Workshop in Clinical Periodontics is summarized.
Abstract
Classification systems are necessary in order to provide a framework in which to scientifically study the etiology, pathogenesis, and treatment of diseases in an orderly fashion. In addition, such systems give clinicians a way to organize the health care needs of their patients. The last time scientists and clinicians in the field of periodontology and related areas agreed upon a classi- fication system for periodontal diseases was in 1989 at the World Workshop in Clinical Periodontics.1 Subsequently, a simpler classification was agreed upon at the 1st European Workshop in Periodontology.2 These classification systems have been widely used by clinicians and research scientists throughout the world. Unfortunately, the 1989 classification had many shortcomings including: 1) considerable overlap in disease categories, 2) absence of a gingival disease component, 3) inappropriate emphasis on age of onset of disease and rates of progression, and 4) inadequate or unclear classification criteria. The 1993 Europea...

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Citations
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Journal ArticleDOI

Anti-Tumor Necrosis Factor-Alpha Therapy and Periodontal Parameters in Patients With Rheumatoid Arthritis

TL;DR: Patients with rheumatoid arthritis receiving anti-TNF-alpha medication had lower periodontal indices and GCF TNF- alpha levels, suggesting suppression of proinflammatory cytokines might prove beneficial in suppressingperiodontal diseases.
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Treatment of multiple adjacent Miller class I and II gingival recessions with a Modified Coronally Advanced Tunnel (MCAT) technique and a collagen matrix or palatal connective tissue graft: a randomized, controlled clinical trial

TL;DR: The present findings indicate that the use of CM may represent an alternative to CTG by reducing surgical time and patient morbidity, but yielded lower CRC than CTG in the treatment of Miller Class I and II MAGR when used in conjunction with MCAT.
Journal ArticleDOI

Toll-like receptors regulate B cell cytokine production in patients with diabetes.

TL;DR: Altered TLR function in B cells from diabetes mellitus patients increases inflammation by two mechanisms: elevation of pro-inflammatory IL-8 and lack of anti-inflammatory/protective IL-10 production.
Journal ArticleDOI

Transcriptomes in Healthy and Diseased Gingival Tissues

TL;DR: A comparison of gene expression signatures between healthy and diseased gingival tissues would provide novel insights in the pathobiology of periodontitis and would inform the design of future studies.
Journal ArticleDOI

Phylogenetic and functional gene structure shifts of the oral microbiomes in periodontitis patients

TL;DR: Functional gene array data showed that a lower gene number but higher signal intensity of major genes existed in periodontitis, and a variety of genes involved in virulence factors, amino acid metabolism and glycosaminoglycan and pyrimidine degradation were enriched in periodentitis, suggesting their potential importance inperiodontal pathogenesis.
References
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Journal ArticleDOI

Natural history of periodontal disease in man. Rapid, moderate and no loss of attachment in Sri Lankan laborers 14 to 46 years of age.

TL;DR: In this paper, the initiation, rate of progress of periodontal disease and consequent tooth loss in a population never exposed to any programs or incidents relative to prevention and treatment of dental diseases was described.
Journal ArticleDOI

Periodontal Diseases: Epidemiology

TL;DR: Although prevalence figures vary with race and geographic region, in most cases, the progression pattern of the disease seems compatible with the retention of a functional dentition throughout life, and most recent data indicate that periodontal disease may confer risk for coronary heart disease and pre-term low birth weight.
Journal ArticleDOI

New concepts of destructive periodontal disease.

TL;DR: Comparison of monitored loss rates for a year with mean loss rates prior to monitoring suggested that there may be relatively short periods in an individual's life in which many sites undergo periodontal destruction followed by periods of extended remission.
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