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Journal ArticleDOI

Development of a Classification System for Periodontal Diseases and Conditions

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TLDR
How the new classification for periodontal diseases and conditions presented in this volume differs from the classification system developed at the 1989 World Workshop in Clinical Periodontics is summarized.
Abstract
Classification systems are necessary in order to provide a framework in which to scientifically study the etiology, pathogenesis, and treatment of diseases in an orderly fashion. In addition, such systems give clinicians a way to organize the health care needs of their patients. The last time scientists and clinicians in the field of periodontology and related areas agreed upon a classi- fication system for periodontal diseases was in 1989 at the World Workshop in Clinical Periodontics.1 Subsequently, a simpler classification was agreed upon at the 1st European Workshop in Periodontology.2 These classification systems have been widely used by clinicians and research scientists throughout the world. Unfortunately, the 1989 classification had many shortcomings including: 1) considerable overlap in disease categories, 2) absence of a gingival disease component, 3) inappropriate emphasis on age of onset of disease and rates of progression, and 4) inadequate or unclear classification criteria. The 1993 Europea...

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Citations
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Journal ArticleDOI

Are cytokines linked to collagen breakdown during periodontal disease progression

TL;DR: The present study showed that EGF was not changed in inflamed gingival tissue and that IL-1beta and IL-4 were particularly and intensively correlated with collagen loss, which could be markers of clinical severity during active periodontitis.
Journal ArticleDOI

Periodontal disease and diabetes mellitus.

TL;DR: A model is presented in which periodontal pathogens may cause increases in proinflammatory cytokines that mediate increases in insulin resistance, resulting in an increase in blood glucose, and this process may be reversed followingperiodontal therapy.
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Detection of herpesviruses and periodontal pathogens in subgingival plaque of patients with chronic periodontitis, generalized aggressive periodontitis, or gingivitis.

TL;DR: This case-control study evaluated the presence of herpes simplex virus type I, EBV-1, human cytomegalovirus (HCMV), Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia in patients with generalized AgP, CP, or gingivitis and in healthy individuals.
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Enamel matrix proteins and bovine porous bone mineral in the treatment of intrabony defects: a comparative controlled clinical trial.

TL;DR: The hypothesis that the adjunctive use of BPBM in grafting intrabony defects has the ability to improve clinical and radiographical outcomes achievable with EMP alone is supported.
Journal ArticleDOI

LPS-stimulated human gingival fibroblasts inhibit the differentiation of monocytes into osteoclasts through the production of osteoprotegerin.

TL;DR: The present study suggests that LPS‐stimulated HGFs inhibit monocyte differentiation into osteoclasts through the production of OPG, and this role of human gingival fibroblasts in osteoclastogenesis regulated by RANKL is clarified.
References
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Journal ArticleDOI

Natural history of periodontal disease in man. Rapid, moderate and no loss of attachment in Sri Lankan laborers 14 to 46 years of age.

TL;DR: In this paper, the initiation, rate of progress of periodontal disease and consequent tooth loss in a population never exposed to any programs or incidents relative to prevention and treatment of dental diseases was described.
Journal ArticleDOI

Periodontal Diseases: Epidemiology

TL;DR: Although prevalence figures vary with race and geographic region, in most cases, the progression pattern of the disease seems compatible with the retention of a functional dentition throughout life, and most recent data indicate that periodontal disease may confer risk for coronary heart disease and pre-term low birth weight.
Journal ArticleDOI

New concepts of destructive periodontal disease.

TL;DR: Comparison of monitored loss rates for a year with mean loss rates prior to monitoring suggested that there may be relatively short periods in an individual's life in which many sites undergo periodontal destruction followed by periods of extended remission.
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