Journal ArticleDOI
Dextroamphetamine. Its cognitive and behavioral effects in normal and hyperactive boys and normal men.
Judith L. Rapoport,Monte S. Buchsbaum,Herbert Weingartner,Theodore P. Zahn,Christine Ludlow,Edwin J. Mikkelsen +5 more
TLDR
Stimulants appear to act similarly on normal and hyperactive prepubertal boys and adults and adults.Abstract:
The effects of a single oral dose of dextroamphetamine sulfate on motor activity, vigilance, learning, and mood were compared for normal and hyperactive prepubertal boys and normal college-aged men using a double-blind crossover design. Both groups of boys and men showed decreased motor activity increased vigilance, and improvement on a learning task after taking the stimulant drug. The men reported euphoria, while the boys reported only feeling "tired# or "different# after taking the stimulant. It is not clear whether this difference in effect on mood between adults and children is due to differing experience with drugs, ability to report affect, or a true pharmacologic age-related effect. While there were some quantitative differences in drug effects on motor activity and vigilance between these different groups, stimulants appear to act similarly on normal and hyperactive children and adults.read more
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BookDOI
Effects of Psychoactive Chemicals on Commercial Driver Health and Performance: Stimulants, Hypnotics, Nutritional, and Other Supplements
TL;DR: Results from the literature review and the two convenience surveys of small numbers of Commercial Driver Medical Examiners and of commercial vehicle stakeholders point to the need for development and provision of more detailed user-friendly information about the numerous chemicals, drugs, supplements, popular energy enhancement products, and other chemical substances that might impact commercial drivers' performance and health.
Journal ArticleDOI
Central Stimulant Treatment of Childhood Attention Deficit Hyperactivity Disorder : Issues and Recommendations from a US Perspective.
TL;DR: The use of CNS stimulants for the treatment of attention deficit hyperactivity disorder (ADHD) in children has steadily increased in most areas of the world over the last 30 years and the treatment has not been shown to change the long term outcome of the disorder.
Journal ArticleDOI
Methylphenidate challenge in a manic boy.
Journal ArticleDOI
Application of Actigraphy in the Clinical Setting: Use in Children With Attention‐Deficit Hyperactivity Disorder
Lucinda G. Miller,Irvin A. Kraft +1 more
TL;DR: The new mini‐motion logger actigraph, which is a wrist‐worn minicomputer, can add an objective element to this assessment and is especially useful in children due to its small size.
Journal ArticleDOI
Differential psychopharmacology of methylphenidate and the neuropsychology of childhood hyperactivity.
TL;DR: A hypothesis is presented to suggest that HAC may be characterized by a trait of excessive variability, and a neural substrate for the abnormal oscillations which characterize HAC is presented in terms of the regulatory functions of the frontal lobe.
References
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Book
Statistical Principles in Experimental Design
TL;DR: In this article, the authors introduce the principles of estimation and inference: means and variance, means and variations, and means and variance of estimators and inferors, and the analysis of factorial experiments having repeated measures on the same element.
Journal ArticleDOI
Statistical Principles in Experimental Design
TL;DR: This chapter discusses design and analysis of single-Factor Experiments: Completely Randomized Design and Factorial Experiments in which Some of the Interactions are Confounded.