Diagnostics of SARS-CoV-2 infection using electrical impedance spectroscopy with an immunosensor to detect the spike protein
Juliana C. Soares,Boda Zhu,Andrey Soares,Monara Kaelle S.C. Angelim,José Luiz Proença-Módena,Pedro M. Moraes-Vieira,Luiz H. C. Mattoso,Osvaldo N. Oliveira +7 more
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In this article, a low-cost immunosensor was used to detect the spike protein of SARS-CoV-2, including in samples of inactivated virus, using electrical impedance spectroscopy.About:
This article is published in Talanta.The article was published on 2021-11-22 and is currently open access. It has received 15 citations till now. The article focuses on the topics: Chemistry & Dielectric spectroscopy.read more
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Electrochemical immunosensors using electrodeposited gold nanostructures for detecting the S proteins from SARS-CoV and SARS-CoV-2
Laís Canniatti Brazaca,Amanda H. Imamura,Nathalia O. Gomes,Mariana B Almeida,Desirée Tamara Scheidt,Paulo A. Raymundo-Pereira,Osvaldo N. Oliveira,Bruno C. Janegitz,Sergio A.S. Machado,Emanuel Carrilho +9 more
TL;DR: In this article , a low-cost (< US$ 0.03 per device) immunosensor based on gold-modified screen-printed carbon electrodes (SPCEs) is presented.
Journal ArticleDOI
Progress in Electrochemical Biosensing of SARS-CoV-2 Virus for COVID-19 Management
TL;DR: This review comprehensively summarizes the state-of-the-art research progress of electrochemical biosensors for COVID-19 diagnosis, which include the detection of spike protein, nucleocapsid protein, whole virus, nucleic acid, and antibodies.
Journal ArticleDOI
An impedimetric biosensor for COVID-19 serology test and modification of sensor performance via dielectrophoresis force
Jiang Zeng,Pedro Augusto Silva Duarte,Yuhao Ma,Oleksandra Savchenko,Lian C. T. Shoute,Yeganeh Khaniani,Shawn Babiuk,Ran Zhuo,Gaser N. Abdelrasoul,Carmen L. Charlton,Jamil N. Kanji,Lorne A. Babiuk,Cole Edward,Jie Chen +13 more
TL;DR: In this article , a gold micro-interdigitated electrodes (IDE) biosensor was used for detecting COVID-19 antibodies using Electrochemical Impedance Spectroscopy (EIS) responses.
Journal ArticleDOI
Immunoassay platform with surface-enhanced resonance Raman scattering for detecting trace levels of SARS-CoV-2 spike protein
Maria Julia Bistaffa,Sabrina A. Camacho,Wallance Moreira Pazin,Carlos J. L. Constantino,Osvaldo N. Oliveira,Pedro H. B. Aoki +5 more
TL;DR: In this paper , a surface-enhanced resonance Raman scattering (SERRS) was used to detect trace levels of SARS-CoV-2 spike (S) protein.
Journal ArticleDOI
Detection of COVID-19-related biomarkers by electrochemical biosensors and potential for diagnosis, prognosis, and prediction of the course of the disease in the context of personalized medicine
Viviana Vásquez,Jahir Orozco +1 more
TL;DR: In this article , the authors discuss electrochemical biosensors for monitoring multiparametric biomarkers at different molecular levels and their potential to elucidate the health status of an individual in a personalized manner.
References
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Impedance Spectroscopy: Applications to Electrochemical and Dielectric Phenomena
TL;DR: In this article, the authors present a detailed overview of electrochemical impedance spectroscopy applications and their applications in the field of biomedical devices and industrial colloids and lubricants, as well as the applications of EIS analysis applications.
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CRISPR-Cas12a-driven MXene-PEDOT:PSS piezoresistive wireless biosensor
TL;DR: This all-in-one detection mode not only bridges the technological gap between biological signal conduction, wireless transmission, and smartphone interface but also improves the portability and the sensitivity (more than one order of magnitude lower than that of traditional CRISPR-Cas12a biosensors).
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Molecular and serological tests for COVID-19. A comparative review of SARS-CoV-2 coronavirus laboratory and point-of-care diagnostics
Robert Kubina,Arkadiusz Dziedzic +1 more
TL;DR: This review summarizes and compares the available POCD and those currently under development, including quantitative reverse transcription PCR (RT-qPCR), serology immunoassays (SIAs) and protein microarray method (PMM) designed for standard and rapid COVID-19 diagnosis.
Journal ArticleDOI
Development of a Portable, Ultra-Rapid and Ultra-Sensitive Cell-Based Biosensor for the Direct Detection of the SARS-CoV-2 S1 Spike Protein Antigen.
TL;DR: The proof-of-concept development of a biosensor able to detect the SARS-CoV-2 S1 spike protein expressed on the surface of the virus is reported, offering a possible solution for the timely monitoring and eventual control of the global coronavirus pandemic.
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Methods of Inactivation of SARS-CoV-2 for Downstream Biological Assays.
Edward I Patterson,Tessa Prince,Enyia R Anderson,Aitor Casas-Sanchez,Shirley L Smith,Cintia Cansado-Utrilla,Tom Solomon,Tom Solomon,Michael J. Griffiths,Michael J. Griffiths,Alvaro Acosta-Serrano,Lance Turtle,Lance Turtle,Grant L. Hughes +13 more
TL;DR: To facilitate the transfer of infectious samples from high-containment laboratories, methods commonly used to inactivate virus are tested and can provide a framework for in-house inactivation of SARS-CoV-2 in other laboratories, ensuring the safe use of samples in lower-cont containment levels.