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Diagnostics of SARS-CoV-2 infection using electrical impedance spectroscopy with an immunosensor to detect the spike protein

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TLDR
In this article, a low-cost immunosensor was used to detect the spike protein of SARS-CoV-2, including in samples of inactivated virus, using electrical impedance spectroscopy.
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This article is published in Talanta.The article was published on 2021-11-22 and is currently open access. It has received 15 citations till now. The article focuses on the topics: Chemistry & Dielectric spectroscopy.

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Progress in Electrochemical Biosensing of SARS-CoV-2 Virus for COVID-19 Management

- 20 Jul 2022 - 
TL;DR: This review comprehensively summarizes the state-of-the-art research progress of electrochemical biosensors for COVID-19 diagnosis, which include the detection of spike protein, nucleocapsid protein, whole virus, nucleic acid, and antibodies.
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An impedimetric biosensor for COVID-19 serology test and modification of sensor performance via dielectrophoresis force

TL;DR: In this article , a gold micro-interdigitated electrodes (IDE) biosensor was used for detecting COVID-19 antibodies using Electrochemical Impedance Spectroscopy (EIS) responses.
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Immunoassay platform with surface-enhanced resonance Raman scattering for detecting trace levels of SARS-CoV-2 spike protein

TL;DR: In this paper , a surface-enhanced resonance Raman scattering (SERRS) was used to detect trace levels of SARS-CoV-2 spike (S) protein.
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Detection of COVID-19-related biomarkers by electrochemical biosensors and potential for diagnosis, prognosis, and prediction of the course of the disease in the context of personalized medicine

TL;DR: In this article , the authors discuss electrochemical biosensors for monitoring multiparametric biomarkers at different molecular levels and their potential to elucidate the health status of an individual in a personalized manner.
References
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Journal ArticleDOI

Information visualization techniques for sensing and biosensing

TL;DR: A suite of software tools, referred to as PEx-Sensors, through which projection techniques are used to analyze electrical impedance spectroscopy data in electronic tongues and related sensors, showing that non-linear projection techniques such as Sammon's Mapping or IDMAP provide higher distinction ability than linear methods for sensor arrays containing units capable of molecular recognition.
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Current and innovative methods for the diagnosis of COVID­19 infection (Review).

TL;DR: In this article, a review of the diagnostic strategies available for the diagnosis of COVID-19 infection in both clinical and research settings is presented, in which the technical and instrumental characteristics of diagnostic methods used are described.
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Ultrasensitive detection of SARS-CoV-2 spike protein in untreated saliva using SERS-based biosensor.

TL;DR: Wang et al. as discussed by the authors proposed a surface enhanced Raman scattering (SERS)-based COVID-19 biosensor for ultrasensitive detection of SARS-CoV-2 virus in untreated saliva.
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Electrochemical immunosensor with Cu 2 O nanocube coating for detection of SARS-CoV-2 spike protein.

TL;DR: In this paper, a label-free electrochemical biosensor was presented as a powerful nanobiodevice for SARS-CoV-2 spike protein detection, which was applied on a screen-printed carbon electrode modified with Cu2O nanocubes (Cu2O NCs), which provided a large surface area in a very small space.
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Ti3C2 MXene nanosheet-based capacitance immunoassay with tyramine-enzyme repeats to detect prostate-specific antigen on interdigitated micro-comb electrode

TL;DR: The interdigitated capacitance immunosensor showed good reproducibility, high specificity and acceptable accuracy for the analysis of human serum specimens in comparison with those obtained from commercial human PSA ELISA kit.