Journal ArticleDOI
Die Umwandlung der Glutaminsäure in Asparaginsäure in den Mitochondrien der Leber. (mit Bemerkung über das Vorkommen einer Transaminase in Clostridium Welchii)
A. F. Müller,F. Leuthardt +1 more
TLDR
In this paper, Homogenat oder Suspensionen von Mitochondrien aus Rattenleber bilden aus Glutaminsaure Asparaginsaure.Abstract:
1. Homogenat oder Suspensionen von Mitochondrien aus Rattenleber bilden aus Glutaminsaure Asparaginsaure. Die Asparaginsaure wurde durch Papierchromatographie nachgewiesen. Malonat hemmt die Reaktion.read more
Citations
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Journal ArticleDOI
The scope of the transamination reaction in animal tissues.
P. S. Cammarata,Philip P. Cohen +1 more
Book ChapterDOI
The Use of Differential Centrifugation in the Study of Tissue Enzymes
Christian de Duve,J. Berthet +1 more
TL;DR: This chapter discusses a new technique of differential centrifugation in the study of cellular organization and the theoretical basis of the technique as well as the various factors of a practical nature.
Journal ArticleDOI
Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain
TL;DR: It is suggested that glutamate may constitute a buffer or bulwark against changes in cerebral amine and ammonia nitrogen, and be placed on the central role of glutamate in the glutamine-glutamate and glutamines-GABA neurotransmitter cycles between neurons and astrocytes.
References
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Journal ArticleDOI
A study of the behaviour of some sixty amino-acids and other ninhydrin-reacting substances on phenol-;collidine' filter-paper chromatograms, with notes as to the occurrence of some of them in biological fluids.
Journal ArticleDOI
Biosynthesis of urea; enzymatic mechanism of arginine synthesis from citrulline.
Sarah Ratner,Anne Pappas +1 more
TL;DR: Glutamic acid was the specific donor in the Borsook-Dubnoff reaction, aspartic acid being utilized only to the extent that it could be converted to glutamic acid.
Journal ArticleDOI
The conversion of citrulline to arginine in kidney
Henry Borsook,Jacob W. Dubnoff +1 more
TL;DR: In the study of this reaction it was observed that glycocyamine was also formed from citrulline and glycine, and no other donor or precursor of the amidine group was found.
Journal ArticleDOI
Urea synthesis by liver homogenates.
Philip P. Cohen,Mika Hayano +1 more
TL;DR: Data will be presented which demonstrate in liver the presence of a potent transimination system which in all probability is the mechanism by which citrulline is converted to arginine in the urea cycle.
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