Journal ArticleDOI
Different types of myocardial necrosis in coronary heart disease: a pathophysiologic review of their functional significance.
Giorgio Baroldi,Giorgio Baroldi +1 more
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TLDR
The incidence as well as the frequent association of three different morphologic patterns of myocardial necrosis suggest that various pathogenetic mechanisms with different biochemical derangements may interact in the natural history of the coronary heart disease.About:
This article is published in American Heart Journal.The article was published on 1975-06-01. It has received 166 citations till now. The article focuses on the topics: Coronary circulation.read more
Citations
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Circadian variation in the frequency of sudden cardiac death.
TL;DR: The finding that the frequency of sudden cardiac death is increased in the morning is compatible with hypotheses that sudden cardiacDeath results from ischemia or from a primary arrhythmic event, and further study of the physiologic changes occurring in theMorning may provide new information supporting or refuting these hypotheses.
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Coronary vasospasm as a possible cause of myocardial infarction. A conclusion derived from the study of "preinfarction" angina.
Attilio Maseri,Antonio L'Abbate,Giorgio Baroldi,Sergio Chierchia,Mario Marzilli,Anna Maria Ballestra,Silva Severi,Oberdan Parodi,Andrea Biagini,Alessandro Distante,A Pesola +10 more
TL;DR: In all 76 patients who underwent hemodynamic monitoring, 201thallium myocardial scintigraphy or angiography during angina, a vasospastic origin of the attacks was documented, and after infarction, complete thrombotic occlusion of the branch shown to undergo vasospasm was documented in two patients by angiographic.
Journal ArticleDOI
The Histopathologic Evolution of Myocardial Infarction
TL;DR: Waviness appears to be due to ischemic injury of fibers and may be the earliest light-microscopic change in evolving myocardial infarction, while myocytolysis does not appear to be related to ischemia per se.
Journal ArticleDOI
Microvascular spasm in the cardiomyopathic Syrian hamster: a preventable cause of focal myocardial necrosis.
TL;DR: It is believed that focal, transient spasm of small blood vessels, probably secondary to vasoactive substances, may cause myocytolytic necrosis (a form of reperfusion injury) in this model.
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Clinical and morphological features of human hypertensive-diabetic cardiomyopathy
TL;DR: The association of diabetes mellitus and hypertension in the absence of significant coronary artery atherosclerosis may lead to a severe cardiomyopathy, which may be secondary to the combined effects of diabetes and hypertension on the myocardium.
References
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Journal ArticleDOI
Factors Influencing Infarct Size Following Experimental Coronary Artery Occlusions
Peter R. Maroko,John K. Kjekshus,Burton E. Sobel,Tan Watanabe,James W. Covell,John Ross,Eugene Braunwald +6 more
TL;DR: It is concluded that the hemodynamic status and neurohumoral background at the time of occlusion and for up to 3 hr thereafter can alter the extent and severity of myocardial ischemic injury andMyocardial necrosis.
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The Speed of Healing of Myocardial Infarcts.
Journal Article
Myocardial Calcium and Magnesium in Acute Ischemic Injury
TL;DR: Investigation of the localization of the increased Ca(--) by cellular fractionation and chemical analysis as well as by electron miscroscopy and microincineration showed that much of it was localized in dense bodies within the mitochondria.
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Modification by Acetylcholine of the Response of Rat Mesenteric Arteries to Sympathetic Stimulation
Kafait U. Malik,George M. Ling +1 more
TL;DR: The aim of this study was to determine the effect of varying concentrations of acetylcholine on the vasoconstriction of the perfused mesenteric arteries of the rat caused by stimulation of their sympathetic postganglionic nerves.