Journal ArticleDOI
Distribution of repair replication in the HeLa cell genome.
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This article is published in International Journal of Radiation Biology.The article was published on 1973-06-01. It has received 16 citations till now. The article focuses on the topics: Genome & HeLa.read more
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Book ChapterDOI
The Repair of DNA Modified by Cytotoxic, Mutagenic, and Carcinogenic Chemicals
TL;DR: This chapter discusses some studies on the interaction of various compounds with cellular DNA and the biochemical and biological consequences of these reactions in a variety of cell systems and focuses attention on DNA as the principal target for a number of chemotherapeutically useful cytotoxic agents and for numerous known carcinogens.
Journal ArticleDOI
Distribution of ultraviolet-induced DNA repair synthesis in nuclease sensitive and resistant regions of human chromatin.
TL;DR: Evidence is provided that the structural constraints placed upon DNA in chromatin also place constraints upon uv-induced DNA repair synthesis in human cells, and the distribution within chromatin of nucleotides incorporated during the slow-repair phase was found to be much more homogeneous.
Journal Article
Nonrandom Nature of in Vivo Methylation by Dimethylnitrosamine and the Subsequent Removal of Methylated Products from Rat Liver Chromatin DNA
TL;DR: It is concluded that the distribution and removal of DMN-induced methylated products in liver chromatin DNA is nonrandom as measured by this technique.
Journal ArticleDOI
Radiofrequency (microwave) radiation exposure of mammalian cells during UV-induced DNA repair synthesis.
TL;DR: Investigation in MRC-5 normal human diploid fibroblasts of the effect of radiofrequency radiation in the microwave range on UV-induced DNA repair found that RFR does not induce DNA repair under these exposure conditions.
References
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Journal ArticleDOI
Repeated Sequences in DNA
Roy J. Britten,D. E. Kohne +1 more
TL;DR: Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms and used in medicine, science, and engineering.
Journal ArticleDOI
Defective repair replication of DNA in xeroderma pigmentosum.
TL;DR: Patients with xeroderma pigmentosum develop fatal skin cancers when exposed to sunlight, and so the failure of DNA repair in the skin must be related to carcinogenesis.
Journal ArticleDOI
Radiation-stimulated dna synthesis in cultured mammalian cells
R. E. Rasmussen,R. B. Painter +1 more
TL;DR: A type of DNA synthesis in mammalian cells that is stimulated by ultraviolet light has been studied by means ofRadioautography and density gradient centrifugation and the presence of bromouracil in the DNA is required before it can be demonstrated by radioautography.
Journal ArticleDOI
Batch procedure for thermal elution of DNA from hydroxyapatite.
Don J. Brenner,Don J. Brenner,George R. Fanning,George R. Fanning,Adrian V. Rake,Adrian V. Rake,Karl E. Johnson,Karl E. Johnson +7 more
TL;DR: A batchwise hydroxyapatite thermal elution method that allows simultaneous handling of up to ten samples is described and was used successfully for fractionating single- and double-stranded DNA in reactions exhibiting low and high levels of reassociation.
Journal ArticleDOI
Repair Replication, Unscheduled DNA Synthesis, and the Repair of Mammalian DNA
R. B. Painter,J. E. Cleaver +1 more
TL;DR: There is at least a rough correlation of the extent of repair replication withThe extent of unscheduled synthesis suggesting that both are manifestations of the same process.
Related Papers (5)
Distribution of deoxyribonucleic acid repair synthesis among repetitive and unique sequences in the human diploid genome.
Two Forms of Repair in the DNA of Human Cells Damaged by Chemical Carcinogens and Mutagens
James D. Regan,R. B. Setlow +1 more