DNA‐dependent RNA polymerases from yeast. Partial characterization of three nuclear enzyme activities
TLDR
Evidence is obtained for the occurrence in sonified yeast extracts of three DNA-dependent RNA polymerases of nuclear origin that differ in their template specificity and in their sensitivity towards cu-amanitin.About:
This article is published in FEBS Letters.The article was published on 1971-11-01 and is currently open access. It has received 44 citations till now. The article focuses on the topics: RNA-dependent RNA polymerase & Polymerase.read more
Citations
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Journal ArticleDOI
Amatoxins, phallotoxins, phallolysin, and antamanide: the biologically active components of poisonous Amanita mushrooms.
Theodor Wieland,Heinz Faulstich +1 more
TL;DR: This review gives a comprehensive account of the molecular toxicology of the bicyclic peptides obtained from the poisonous mushrooms of the genus Amanita, also including the most important analytical data.
Journal ArticleDOI
Studies on rna synthesis in two populations of nuclei from the mammalian cerebral cortex
TL;DR: No qualitative difference in the number of enzymes involved in RNA synthesis in neuronal and glial cell nuclei has been found, but there are quantitative differences in activity between the two nuclear populations.
Book ChapterDOI
Mammalian RNA polymerases.
TL;DR: The chapter concludes that finally, the factors that are involved in initiation, termination and release of RNA chains in eukaryotic cells should be explored.
Journal ArticleDOI
Immunological studies of yeast nuclear RNA polymerases at the subunit level
TL;DR: Inhibition studies with these subunit-specific antibodies showed that the common subunits are not always similarly exposed to antibody attack within the three enzymes, which indicates the structural similarity, organization and evolution of eukaryotic RNA polymerases.
Journal ArticleDOI
Mode of Action of Thiolutin, an Inhibitor of Macromolecular Synthesis in Saccharomyces cerevisiae
A. Jimenez,Donald J. Tipper,Donald J. Tipper,Donald J. Tipper,Julian Davies,Julian Davies,Julian Davies +6 more
TL;DR: The sulfur-containing antibiotic thiolutin has been shown to be a potent, reversible inhibitor of the growth of Saccharomyces cerevisiae and may prove to be of use in studies of various stages of yeast growth.
References
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Journal ArticleDOI
Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms
TL;DR: Three distinct RNA polymerase activities have been isolated from developing sea urchin embryos, and in rat liver nuclei there are two RNA polymerases activities.
Journal ArticleDOI
α-Amanitin: A specific inhibitor of one of two DNA-dependent RNA polymerase activities from calf thymus
Claude Kedinger,Claude Kedinger,M. Gniazdowski,M. Gniazdowski,Jean-Louis Mandel,Jean-Louis Mandel,F. Gissinger,F. Gissinger,Pierre Chambon,Pierre Chambon +9 more
TL;DR: α-amanitin selectively inhibits RNA synthesis catalyzed by calf thymus RNA polymerase activity B by interacting with the enzyme and inhibiting chain elongation as discussed by the authors, which can be used to identify the source of RNA synthesis.
Journal ArticleDOI
Specific Nucleolar and Nucleoplasmic RNA Polymerases
TL;DR: It is concluded that the RNA polymerases are specifically localized within the nucleus and may, therefore, play specific roles in the regulation of genetic transcription.
Journal ArticleDOI
Structure and Regulatory Properties of Eucaryotic RNA Polymerase
S. P. Blatti,C. J. Ingles,T. J. Lindell,P. W. Morris,R. F. Weaver,F. Weinberg,William J. Rutter +6 more
Journal ArticleDOI
Different responses of soluble whole nuclear RNA polymerase and soluble nucleolar RNA polymerase to divalent cations and to inhibition by α-ananitin
TL;DR: It has been concluded that the RNA polymerase of nucleoli differs structurally from the chromatin-associated polymerase extractable from whole nuclei.