Dose-intensive therapy for extensive-stage small cell lung cancer and extrapulmonary small cell carcinoma: long-term outcome.
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TLDR
It is concluded that high-dose therapy is not indicated as an approach for ES SCLC, except as part of an investigative trial, and factors associated with more favorable overall survival were the use of a more aggressive induction regimen (ICE), and the EPSC histology.About:
This article is published in Biology of Blood and Marrow Transplantation.The article was published on 2002-06-01 and is currently open access. It has received 7 citations till now. The article focuses on the topics: Survival rate & Small-cell carcinoma.read more
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Journal ArticleDOI
Small cell cancer of the bladder: pathology, diagnosis, treatment and prognosis
N. Ismaili,Samia Arifi,Aude Flechon,O. El Mesbahi,Jean-Yves Blay,Jean-Pierre Droz,Hassan Errihani +6 more
TL;DR: This paper would provide a comprehensive review of the epidemiology, clinical features, diagnosis, pathologic features, histogenesis, molecular genetics, staging, treatment, and prognosis of SCCB.
Journal ArticleDOI
High-Dose Chemotherapy Followed by Autologous Hematopoietic Stem-Cell Transplantation for the Treatment of Solid Tumors in Adults: A Critical Review
TL;DR: The use of HDCT with autologous HSCT may improve tumor response rates and/or possibly progression-free survival, especially in some selected patient subgroups, but this strategy did not demonstrate in almost all cases to produce significantly higher cure rates than standard-dose chemotherapy.
Journal ArticleDOI
Standard versus dose-intensified chemotherapy with sequential reinfusion of hematopoietic progenitor cells in small cell lung cancer patients with favorable prognosis.
TL;DR: Patients receiving ICT with filgrastim achieved significant increases in median survival and TTP despite an increased need for transfusions despite the need for platelet and red blood cell transfusions.
Journal ArticleDOI
Stem-cell transplantation for the treatment of advanced solid tumors
TL;DR: The results of the main phase II and III studies of HDC with ASCT, as well as the preliminary experience using allogeneic transplantation for solid tumors are reviewed.
Journal ArticleDOI
Updates in small cell lung cancer treatment.
TL;DR: An overview of SCLC is provided, including current treatment strategies for limited, extensive, and recurrent disease, by understanding the various traditional and emerging treatment modalities, so nurses can better assess their patients and help to reduce potential S CLC treatment complications.
References
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Book ChapterDOI
Nonparametric Estimation from Incomplete Observations
Edward L. Kaplan,Paul Meier +1 more
TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Journal ArticleDOI
A multiple testing procedure for clinical trials.
TL;DR: The overall size of the procedure is shown to be controlled with virtually the same accuracy as the single sample chi-square test based on N(m1 + m2) observations and the power is found to bevirtually the same.
Book
analysis of binary data
David Cox,E. J. Snell +1 more
TL;DR: Binary response variables special logistical analyses some complications some related approaches more complex responses.
Journal ArticleDOI
Mobilization of tumor cells and hematopoietic progenitor cells into peripheral blood of patients with solid tumors [see comments]
TL;DR: There is a high proportion of patients with circulating tumor cells under steady-state conditions, and in addition a substantial risk of concomitant tumor cell recruitment upon mobilization of PBPCs, particularly in stage IV breast cancer patients with bone marrow infiltration.