Open AccessJournal Article
EEG profile and behavioral changes after a single dose of clozapine in normals and schizophrenics.
J Roubicek,I Major +1 more
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TLDR
The EEG changes after clozapine, especially when instrumentally quantified, demonstrated the predictive value of EEG, which indicated its possible thymoleptic effect with therapeutic studies in depression.About:
This article is published in Biological Psychiatry.The article was published on 1977-10-01 and is currently open access. It has received 34 citations till now. The article focuses on the topics: Electroencephalography.read more
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Clozapine. A novel antipsychotic agent.
TL;DR: This review considers the discovery of clozapine; its chemistry, pharmacologic activities, metabolism, and pharmacokinetics; evidence of its efficacy; and its side effects and appropriate clinical use.
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Clozapine. A review of its pharmacological properties, and therapeutic use in schizophrenia.
Andrew Fitton,Rennie C. Heel +1 more
TL;DR: Clozapine therapy, performed in conjunction with close haematological monitoring, is indicated for the management of severe and chronic schizophrenia refractory to classic antipsychotic therapy, and in those unable to tolerate such therapy.
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EEG abnormalities during treatment with typical and atypical antipsychotics.
Franca Centorrino,Bruce H. Price,Margaret Tuttle,Won-Myong Bahk,John Hennen,Matthew J. Albert,Ross J. Baldessarini +6 more
TL;DR: In this article, the authors examined the risk of EEG abnormalities associated with various antipsychotic drugs, including clozapine, olanzapine and quetiapine.
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Recent Studies of Psychophysiology in Schizophrenia
Herbert E. Spohn,Terry Patterson +1 more
TL;DR: The review concludes with the recommendation that peripheral psychophysiological studies entailing comprehensive recording of brain electrical activity and behavioral experimentation on variables thought to be influenced by schizophrenia are promising directions for future research.
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Clozapine: a clinical review of adverse effects and management.
Mohammad Masud Iqbal,Atiq Rahman,Zahid Husain,Syed Zaber Mahmud,William G. Ryan,Jacqueline Maus Feldman +5 more
TL;DR: The history, pharmacology, management of side effects, and fetal and neonatal effects of clozapine are covered, which have resulted in the expansion of its use from refractory schizophrenia to schizoaffective disorders, affective disorders, some neurological disorders, aggression, as well as psychosis in patients with dementia and parkinsonism.