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Journal ArticleDOI

Effect of selective inhibitors of tyrosine and tryptophan hydroxylases on self-stimulation in the rat

TLDR
Measurement of amine levels suggested that catecholamine depletion was more influential at increasing the self-timulation threshold than serotonin depletion, and data suggest that both catecholicamines and serotonin are involved in pathways for self-stimulating drive-reward.
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This article is published in Experimental Neurology.The article was published on 1970-05-01. It has received 54 citations till now. The article focuses on the topics: Reserpine & Tyrosine Hydroxylase Inhibitor.

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Ethanol Self-Administration Restores Withdrawal-Associated Deficiencies in Accumbal Dopamine and 5-Hydroxytryptamine Release in Dependent Rats

TL;DR: It is suggested that deficits in accumbal monoamine release may contribute to the negative affective consequences ethanol withdrawal and, thereby, motivate ethanol-seeking behavior in dependent subjects.
Journal ArticleDOI

Catecholamine systems as the neural substrate for intracranial self-stimulation: a hypothesis.

TL;DR: Brain sites that support ICSS in the rat were found to be highly correlated with electrodes in 3 major CA systems: the mesolimbic and nigrostriatal dopaminergic systems and the dorsal noradrenergic system.
Book

Cortico-Hippocampal Interplay and the Representation of Contexts in the Brain

Robert Miller
TL;DR: The Septum as a Pacemaker for the Hippocampal Theta Rhythm and Towards a Neuronal Model to Account for the Laminar Waveforms of Theta Activity are studied.
Journal ArticleDOI

Catecholamine-containing neurones and electrical self-stimulation. 1. A review of some data.

TL;DR: The hypothesis is advanced that electrical self-stimulation results in the majority of cases from activation of one or both of these catecholamine-containing systems.
Journal ArticleDOI

Effects on self-stimulation behavior of drugs influencing dopaminergic neurotransmission mechanisms.

TL;DR: The results suggest that, in addition to noradrenaline, the integrity of central dopaminergic systems may be essential for the behavioral expression of certain motivational processes.
References
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Journal ArticleDOI

Dynamic response of chest wall and lung injuries in rabbits exposed to air shock waves of short duration.

TL;DR: The chest walls of rabbits exposed to steep-fronted air shock waves of short duration produced by 50 g spherical charges of TNT were recorded by means of a mechano-electric motion transducer to study the correlation between the deformations of the chest and the damage inflicted to the underlying organs, especially the lungs.
Journal Article

p-CHLOROPHENYLALANINE: A SPECIFIC DEPLETOR OF BRAIN SEROTONIN

TL;DR: The results suggest that p -chlorophenylalanine may effect 5HT depletion by inhibiting the biosynthesis of this monoamine, possibly by blocking tryptophan hydroxylation.
Journal ArticleDOI

Demonstration and mapping out of nigro-neostriatal dopamine neurons

TL;DR: The data give strong evidence for the existence of nigro-neostriatal dopamine neurons, which probably contain most or all of the dopamine present in the neostriatum.
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