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Effects of electric currents on bone in vivo.

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This article is published in Nature.The article was published on 1964-11-14. It has received 495 citations till now.

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The biology of fracture healing in long bones

TL;DR: This review is primarily concerned with those features which have direct clinical relevance and it is fortunately possible to treat fractures successfully without a complete understanding of the cellular mechanisms involved without at the same time relying entirely on empiricism.
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Bone remodeling I: theory of adaptive elasticity

TL;DR: A thermomechanical continuum theory involving a chemical reaction and mass transfer between two constituents is developed in this article as a model for bone remodeling, which describes an elastic material which adapts its structure to applied loading.
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Bone development and its relation to fracture repair. The role of mesenchymal osteoblasts and surface osteoblasts.

TL;DR: This review demonstrates the repetitive nature of woven to lamellar bone formation as mediated by MOBLs and SOBLs in both normal vertebrate bones and bone repair.
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The stimulation of bone growth by ultrasound.

TL;DR: Pulsed ultrasound, in the form of short bursts, was used at low intensities (below cavitation threshold) so that the temperature variation, at the osteotomy site, was of the order of 0.01° C a fact that reinforces the assumption that the stimulation mechanism due to the appearence of electric potentials is of non-thermal origin such as that caused by piezoelectricity.
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Augmentation of Bone Repair by Inductively Coupled Electromagnetic Fields

TL;DR: The induced voltage field in bone appears to increase the organization and strength of the repair process at 28 days after "fracture" in canine osteotomies.
References
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Journal ArticleDOI

On the piezoelectric effect of bone

TL;DR: In this paper, the authors measured the piezoelectric effect of bone and found that the maximum value of the PDE was 6×10 -9 c.s.u.
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Generation of Electric Potentials by Bone in Response to Mechanical Stress

TL;DR: The amplitude of electrical potentials generated in stressed bone is dependent upon the rate and magnitude of bony deformation, while polarity is determined by the direction of bending, while areas under compression develop negative potentials with respect to other areas.
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Piezoelectric effect in bone.

TL;DR: There is convincing evidence that bone has an orderly morphological and microscopic structure that might be expected to exhibit piezoelectric properties, as in the case of many other multicrystalline structures.
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Electro-kinetic properties of cells in growth processes. I. The electrophoretic behavior of liver cells during regeneration and post-natal growth.

TL;DR: A rapid increase in the electrophoretic mobility was observed beginning almost immediately after partial hepatectomy, reaching a peak in the course of 12–48 hr and returning to normal values upon termination of the restorative process.
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Electron paramagnetic resonance in non-irradiated bone.

TL;DR: The semiconduction theory has recently been reported on in more detail and evidence presented for the formation of multiple pn junctions from the apatite crystal (p type) collagen fibre (n type) in the bone matrix.
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