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Journal ArticleDOI

Effects of phosphotungstic acid and silicotungstic acid on respiration and integrity of rat liver mitochondria.

TLDR
The results clearly show that PTA and STA are not biochemically inert and probably have more than a single mitochondrial site of action.
About
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1970-02-06. It has received 9 citations till now. The article focuses on the topics: Phosphotungstic acid & Silicotungstic acid.

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Book ChapterDOI

Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues.

TL;DR: The chapter represents the most detailed account of preparative procedures available for mitochondria and submitochondrial particles of rat liver and presents flow diagrams that include many of the methods to obtain an overall view of a given procedure.
Journal ArticleDOI

Biochemical and ultrastructural properties of a mitochondrial inner membrane fraction deficient in outer membrane and matrix activities.

TL;DR: Treatment of the inner membrane matrix fraction of rat liver mitochondria with the nonionic detergent Lubrol WX solubilized about 70% of the total protein and 90% or more of the following matrix activities: malate dehydrogen enzyme, glutamate dehydrogenase, and isocitrate dehydrationase (NADP).
Journal ArticleDOI

Does speciation matter for tungsten ecotoxicology

TL;DR: The available toxicological information from the standpoint of tungsten speciation is reviewed and knowledge gaps are identified and pertinent future research directions are identified.
References
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Journal ArticleDOI

Enzymatic properties of the inner and outer membranes of rat liver mitochondria

TL;DR: The inner membrane-matrix fraction retained a high degree of morphological and biochemical integrity and exhibited a high respiratory rate and respiratory control when assayed in a sucrose-mannitol medium containing EDTA.
Journal ArticleDOI

Cell-membrane ultrastructure. Low-temperature electron microsopy and x-ray diffraction studies of lipoprotein components in lamellar systems.

TL;DR: The combined electron-microscope and biochemical evidence regarding mitochondria and mitochondrial fractions indicates that all the functional enzymatic components of the electron-transport chain are compactly arranged in the “elementary particle,” which may therefore be regarded as the ultimate unit of mitochondrial function.
Journal ArticleDOI

Partial resolution of the enzymes catalyzing oxidative phosphorylation. X. Correlation of morphology and function in submitochondrial particles.

TL;DR: Evidence has been presented which greatly strengthens the suggestion that the spherical particles lining the inner membranes of mitochondria are the morphological representations of coupling factor 1 (ATPase).
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