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Effects of prolonged administration of pimozide on sleep-EEG patterns in psychiatric patients.

Gillin Jc, +3 more
- 01 Jan 1977 - 
- Vol. 1, Iss: 3, pp 225-232
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This article is published in Communications in psychopharmacology.The article was published on 1977-01-01 and is currently open access. It has received 11 citations till now. The article focuses on the topics: Sleep in non-human animals & Pimozide.

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Sleep disturbances in patients with schizophrenia : impact and effect of antipsychotics.

TL;DR: It appears possible that the high-potency drugs exert their effects on sleep in schizophrenic patients, for the most part, in an indirect way by suppressing stressful psychotic symptomatology.
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Drug effects on REM sleep and on endogenous depression

TL;DR: The present study reviewed literature from 1962 to 1989 on drug REM sleep effects to examine the hypothesis that drugs producing arousal-type RSD improve endogenous depression, and indicated that all drugs producing arousing RSD improved endogenous depression.
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Sleep-promoting properties of quetiapine in healthy subjects

TL;DR: The sleep-improving properties of quetiapine may be important in counteracting different aspects of psychopathology in schizophrenia and other disorders and other mechanisms might be relevant as well and further investigation is required.
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Sleep in schizophrenic patients on and off haloperidol therapy. Clinically stable vs relapsed patients.

TL;DR: The state-dependent contribution of neuroleptic withdrawal and psychotic relapse in influencing sleep measures is examined and the level of psychosis was inversely correlated with sleep efficiency, total sleep time, and stage 4 sleep in the drug-free patients.
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Effects of antipsychotic treatment on polysomnographic measures in schizophrenia: a replication and extension.

TL;DR: These data demonstrate partial improvement of some but not all EEG sleep measures in schizophrenic patients through the course of neuroleptic treatment and suggest that shortened REM latency and disturbed sleep continuity might represent reversible state abnormalities, while reduced slow-wave sleep may represent a more persistent trait abnormality in schizophrenia.
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