Journal ArticleDOI
Effects of Selected Phenothiazines on REM Sleep in Schizophrenics
TLDR
These studies have not consistently demonstrated marked differences in REM sleep between schizophrenics and normal subjects, and several recent studies have suggested, however, that Stage 4 or delta sleep may be decreased in schizophrenia 4 and depressive psychosis.Abstract:
SINCE THE discovery of rapid eye movements (REMs) associated with a desynchronized electroencephalogram (EEG) during behavioral sleep 1 and the correlation of this sleep stage with dreaming, 2 considerable investigation of REM sleep has been instituted to assess its significance in normal man and in various psychiatric illnesses. The similarity between mentation during dreaming in normal people and thought patterns in schizophrenia has led to many investigations of REM sleep in this disease. These studies have not consistently demonstrated marked differences in REM sleep between schizophrenics and normal subjects. 3 Similarly, REM sleep does not appear to be markedly altered in mental illness characterized primarily by depression. 3 Several recent studies have suggested, however, that Stage 4 or delta sleep may be decreased in schizophrenia 4 and depressive psychosis. 5,6 Various drugs used in the treatment of mental illness have beenread more
Citations
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Journal ArticleDOI
Sleep disturbances in patients with schizophrenia : impact and effect of antipsychotics.
TL;DR: It appears possible that the high-potency drugs exert their effects on sleep in schizophrenic patients, for the most part, in an indirect way by suppressing stressful psychotic symptomatology.
Journal ArticleDOI
Sleep in schizophrenia patients and the effects of antipsychotic drugs
Jaime M. Monti,Daniel Monti +1 more
TL;DR: The sleep disturbances of either never-medicated or previously treated schizophrenia patients are characterized by a sleep-onset and maintenance insomnia, and the atypical antipsychotics olanzapine, risperidone, and clozapine significantly increase total sleep time and stage 2 sleep.
Journal ArticleDOI
Electroencephalographic sleep abnormalities in schizophrenia. Relationship to positive/negative symptoms and prior neuroleptic treatment.
Rajiv Tandon,James E. Shipley,Stephan F. Taylor,John F. Greden,Alan S. Eiser,John R. DeQuardo,JoAnn Goodson +6 more
TL;DR: Electroencephalographic sleep in drug-naive and previously medicated schizophrenics had significantly greater impairment of sleep continuity and shorter rapid eye movement latency when compared with controls, and findings were significantly influenced by duration of drug-free status.
Journal ArticleDOI
Sleep-promoting properties of quetiapine in healthy subjects
Stefan Cohrs,Andrea Rodenbeck,Zhenghua Guan,Kathrin Pohlmann,Wolfgang Jordan,Andreas Meier,Eckart Rüther +6 more
TL;DR: The sleep-improving properties of quetiapine may be important in counteracting different aspects of psychopathology in schizophrenia and other disorders and other mechanisms might be relevant as well and further investigation is required.
Journal ArticleDOI
Sleep in psychiatric disorders
TL;DR: Although sleep patterns are not necessarily diagnostic of particular psychiatric disorders, there are relationships between certain sleep abnormalities and categories of psychiatric disorders.
References
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Journal ArticleDOI
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