Journal ArticleDOI
Elevated glycosidases and proteolytic enzymes in cells transformed by RNA tumor virus.
TLDR
Activities of 9 glycosidases were found to be significantly elevated in MSV-3T3 and RSV- 3T3 cells compared to 3T2 cells; acid phosphatase and β-glucuronidase levels were similar in the normal and RNA virus transformed cells.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1972-04-21. It has received 108 citations till now. The article focuses on the topics: RNA & RNA virus.read more
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Book ChapterDOI
Cellular adhesiveness and extracellular substrata.
TL;DR: Adhesiveness is common to many different cell types under a variety of conditions, and the underlying mechanisms are analogous for active cell-substratum adhesion occurring in vitro to artificial and to model physiological substrata and in vivo to fibr inogen or fibrin deposits.
Journal ArticleDOI
Cell surface proteins and malignant transformation.
TL;DR: Evidence concerning the reasons for these alterations and the possible functions of some of the molecules is reviewed, and particular emphasis is placed on the idea that surface molecules are associated in specific non-covalent complexes which are important for their functions.
Journal ArticleDOI
Cancer metastasis. Organ colonization and the cell-surface properties of malignant cells.
Journal ArticleDOI
Trans-membrane control of the receptors on normal and tumor cells. II. Surface changes associated with transformation and malignancy.
Journal ArticleDOI
Enzyme Activity in Invasive Tumors of Human Breast and Colon
H B Bosmann,T C Hall +1 more
TL;DR: Elevated levels of glycoprotein:sialyltransferase activity were found in human malignant neoplastic tissues compared to normal, benign, and "preneoplastic" tissues, and changes in the activity of degradative enzymes may be associated with tumor invasiveness and maintenance of the neoplastics state.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Restoration of Normal Growth by Covering of Agglutinin Sites on Tumour Cell Surface
Max M. Burger,Kenneth D. Noonan +1 more
TL;DR: By covering sites on transformed cells with monovalent concanavalin A, the growth pattern of transformed fibroblasts is restored to that of normal cells.
Journal ArticleDOI
Structural difference in sites on the surface membrane of normal and transformed cells.
Michael Inbar,Leo Sachs +1 more
TL;DR: About 85 per cent of binding sites for the protein concanavalin A that are exposed on the surface membrane of transformed cells, are in a cryptic form on normal cells.
Journal ArticleDOI
Glycopeptides from the surface of control and virus-transformed cells.
TL;DR: The elution profiles suggest that there are differences in the glycopeptides from the surface of control cells and those from transformed cells.
Journal ArticleDOI
Different locations of carbohydrate-containing sites in the surface membrane of normal and transformed mammalian cells
TL;DR: A soybean Agglutinin was found to agglutinate mouse, rat and human cell lines transformed by viral carcinogens, but not hamster cells transformed by Viral or non-viral carcinogens.