ERC-ESICM guidelines on temperature control after cardiac arrest in adults
Claudio Santoni,Jerry P. Nolan,Lars W. Andersen,Bernd W. Böttiger,Alain Cariou,Tobias Cronberg,Hans Friberg,Cornelia Genbrugge,Gisela Lilja,Peter T. Morley,Nikolaos Nikolaou,Theresa M. Olasveengen,Markus B. Skrifvars,Fabio Silvio Taccone,Jasmeet Soar +14 more
TLDR
In this article , the authors provide evidence-based guidance for temperature control in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying cardiac rhythm.Abstract:
The aim of these guidelines is to provide evidence‑based guidance for temperature control in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying cardiac rhythm. These guidelines replace the recommendations on temperature management after cardiac arrest included in the 2021 post-resuscitation care guidelines co-issued by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM). The guideline panel included thirteen international clinical experts who authored the 2021 ERC-ESICM guidelines and two methodologists who participated in the evidence review completed on behalf of the International Liaison Committee on Resuscitation (ILCOR) of whom ERC is a member society. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations. The panel provided suggestions on guideline implementation and identified priorities for future research. The certainty of evidence ranged from moderate to low. In patients who remain comatose after cardiac arrest, we recommend continuous monitoring of core temperature and actively preventing fever (defined as a temperature > 37.7 °C) for at least 72 h. There was insufficient evidence to recommend for or against temperature control at 32-36 °C or early cooling after cardiac arrest. We recommend not actively rewarming comatose patients with mild hypothermia after return of spontaneous circulation (ROSC) to achieve normothermia. We recommend not using prehospital cooling with rapid infusion of large volumes of cold intravenous fluids immediately after ROSC. read more
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Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial
TL;DR: In this paper , the effect of hypothermic temperature control after in-hospital cardiac arrest (IHCA) on mortality and functional outcome as compared with normothermia was evaluated in 11 hospitals in Germany.
Journal ArticleDOI
Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial
Sebastian Wolfrum,Kevin Roedl,Alexia S. Hanebutte,Rüdiger Pfeifer,Volkhard Kurowski,Reimer Riessen,Anne Daubmann,Stephan Braune,Gerold Söffker,E. Bibiza-Freiwald,Karl Wegscheider,Heribert Schunkert,Holger Thiele,Stefan Kluge +13 more
TL;DR: The HACA-IHCA (Hypothermia After In-Hospital Cardiac Arrest) trial was underpowered and may have failed to detect clinically important differences between hypothermic temperature control and normothermia.
Journal ArticleDOI
EEG monitoring after cardiac arrest
TL;DR: EEG is a useful tool to assess the severity of HIBI and provide prognostic information, and can be used to diagnose epileptiform activity in patients with suspected seizures and monitor the effectiveness of antiepileptic treatment.
Journal ArticleDOI
Temperature control in adults after cardiac arrest: a survey of current clinical practice in Germany
Kevin Roedl,Sebastian Wolfrum,Guido Michels,Martin Pin,Gerold Söffker,Uwe Janssens,Stefan Kluge +6 more
TL;DR: In this article , a survey targeting members of three medical emergency and critical care societies in Germany (April 21-June 6, 2022) assessed post-cardiac arrest temperature control management.
Journal ArticleDOI
Temperature control after cardiac arrest: friend or foe
Jerry P. Nolan,Jasmeet Soar +1 more
TL;DR:
References
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TL;DR: This randomized, controlled trial compared the effects of moderate hypothermia and normothermia in patients who remained unconscious after resuscitation from out-of-hospital cardiac arrest to survive to hospital discharge and be discharged to home or to a rehabilitation facility.
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Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest
Michael Holzer,Fritz Sterz,J. M. Darby,S. A. Padosch,Karl B. Kern,Bernd W. Böttiger,Kees H. Polderman,Armand R. J. Girbes,Michael Holzer,Stephen Bernard,M. D. Buist,Peter Safar,Patrick M. Kochanek +12 more
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Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia☆
TL;DR: Treatment with moderate hypothermia appears to improve outcomes in patients with coma after resuscitation from out-of-hospital cardiac arrest, according to preliminary observations.