R
Reimer Riessen
Researcher at University of Tübingen
Publications - 141
Citations - 3404
Reimer Riessen is an academic researcher from University of Tübingen. The author has contributed to research in topics: Intensive care & Medicine. The author has an hindex of 24, co-authored 118 publications receiving 2859 citations.
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Journal ArticleDOI
Paclitaxel Inhibits Arterial Smooth Muscle Cell Proliferation and Migration In Vitro and In Vivo Using Local Drug Delivery
Dorothea I. Axel,W. Kunert,Christoph Göggelmann,Martin Oberhoff,Christian Herdeg,Axel Küttner,Doris H. Wild,Bernhard R. Brehm,Reimer Riessen,Gerhard Köveker,Karl R. Karsch +10 more
TL;DR: Paclitaxel inhibits haSMC proliferation and migration in a dose-dependent manner in monocultures and cocultures even in the presence of mitogens, and prevents neointima formation in rabbits after balloon angioplasty.
Journal ArticleDOI
Low-Dose Radioactive Endovascular Stents Prevent Smooth Muscle Cell Proliferation and Neointimal Hyperplasia in Rabbits
Christoph Hehrlein,Christina Gollan,Klaus Dönges,Jürgen Metz,Reimer Riessen,Peter Fehsenfeld,Eberhard von Hodenberg,Wolfgang Kübler +7 more
TL;DR: It is clearly indicated that low-dose radioactive endovascular stents potently inhibit SMC proliferation and neointimal hyperplasia in rabbits.
Journal ArticleDOI
Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis: A Randomized Trial
Frank M. Brunkhorst,Michael Oppert,Gernot Marx,Frank Bloos,Katrin Ludewig,Christian Putensen,Axel Nierhaus,Ulrich Jaschinski,Andreas Meier-Hellmann,Andreas Weyland,Matthias Gründling,Onnen Moerer,Reimer Riessen,Armin Seibel,Maximilian Ragaller,Markus W. Büchler,Stefan John,Friedhelm Bach,Claudia Spies,Lorenz Reill,Harald Fritz,Michael Kiehntopf,Evelyn Kuhnt,Holger Bogatsch,Christoph Engel,Markus Loeffler,Marin H. Kollef,Konrad Reinhart,Tobias Welte +28 more
TL;DR: In this paper, the authors compared the effect of moxifloxacin and meropenem with the effect on sepsis-related organ dysfunction and concluded that meropenems alone did not result in less organ failure.
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Impact of compliance with infection management guidelines on outcome in patients with severe sepsis: a prospective observational multi-center study
Frank Bloos,Daniel Thomas-Rüddel,Hendrik Rüddel,Christoph Engel,Daniel Schwarzkopf,John C. Marshall,Stéphan Juergen Harbarth,Philipp Simon,Reimer Riessen,Didier Keh,Karin Dey,Manfred Weiß,Susanne Toussaint,Dirk Schädler,Andreas Weyland,Maximillian Ragaller,Konrad Schwarzkopf,Jürgen Eiche,Gerhard Kuhnle,Heike Hoyer,Christiane S. Hartog,Udo Kaisers,Konrad Reinhart +22 more
TL;DR: A delay in source control beyond 6 hours may have a major impact on patient mortality, and adequate AT is associated with improved patient outcome but compliance with guideline recommendation requires improvement.
Journal ArticleDOI
Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial
Frank Bloos,Hendrik Rüddel,Daniel Thomas-Rüddel,Daniel Schwarzkopf,Christine Pausch,Stéphan Juergen Harbarth,Torsten Schreiber,Matthias Gründling,John Marshall,Philipp Simon,Mitchell M. Levy,Manfred Weiss,Andreas Weyland,Herwig Gerlach,Tobias Schürholz,Christoph Engel,Claudia Matthäus-Krämer,Christian Scheer,Friedhelm Bach,Reimer Riessen,Bernhard Poidinger,Karin Dey,Norbert Weiler,Andreas Meier-Hellmann,Helene Häberle,Gabriele Wöbker,Udo Kaisers,Konrad Reinhart +27 more
TL;DR: Delay in antimicrobial Therapy and source control was associated with increased mortality but the multifaceted approach was unable to change time to antimicrobial therapy in this setting and did not affect survival.