Journal ArticleDOI
Error in medicine: what have we learned?
David W. Bates,Atul A. Gawande +1 more
TLDR
In this paper, the authors discuss several books on the continuing discovery of the frequency and effect of medical errors, and present a survey of the literature on medical errors and their effects.Abstract:
This essay discusses several books on the continuing discovery of the frequency and effect of medical errors.read more
Citations
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Journal ArticleDOI
Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review
TL;DR: The results suggest that drug therapy based on individuals' genetic makeups may result in a clinically important reduction in adverse outcomes and serve as a foundation for further research on how pharmacogenomics can reduce the incidence of adverse reactions and on the resulting clinical, societal, and economic implications.
Journal ArticleDOI
Measuring errors and adverse events in health care
Eric J. Thomas,Laura A. Petersen +1 more
TL;DR: 8 methods used to measure errors and adverse events in health care and their strengths and weaknesses are identified and a general framework to help health care providers, researchers, and administrators choose the most appropriate methods to meet their patient safety measurement goals is proposed.
Journal ArticleDOI
Statistical assessment of the learning curves of health technologies.
TL;DR: Systematically to identify 'novel' statistical techniques applied to learning curve data in other fields, such as psychology and manufacturing and to test these statistical techniques in data sets from studies to assess health technologies in which learning curve effects are known to exist.
Journal ArticleDOI
Conceptual frameworks for health systems performance: a quest for effectiveness, quality, and improvement
TL;DR: This paper explores the conceptual bases, effectiveness and its indicators, as well as the quality improvement dynamics of the performance frameworks of the UK, Canada, Australia, US, World Health Organization, and Organisation for Economic Co-operation and Development.
Journal ArticleDOI
An evaluation of risk factors for adverse drug events associated with angiotensin‐converting enzyme inhibitors
Takeshi Morimoto,Takeshi Morimoto,Takeshi Morimoto,Tejal K. Gandhi,Tejal K. Gandhi,Julie M. Fiskio,Andrew C. Seger,Joseph W. So,E. Francis Cook,E. Francis Cook,Tsuguya Fukui,David W. Bates,David W. Bates +12 more
TL;DR: Cox proportional hazard model identified the following independent risk factors for discontinuation because of adverse drug events: age, female gender, ethnicity other than African American or Latino, no history of previous ACE inhibitor use, history of cough caused by another ACE inhibitor, hypertension, anxiety or depression, no hemodialysis, and elevated creatinine.
References
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Journal ArticleDOI
Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I.
Troyen A. Brennan,Lucian L. Leape,Nan M. Laird,Liesi E. Hebert,A R Localio,Ann G. Lawthers,Joseph P. Newhouse,Paul C. Weiler,Howard H. Hiatt +8 more
TL;DR: There is a substantial amount of injury to patients from medical management, and many injuries are the result of substandard care.
Journal ArticleDOI
A multifactorial intervention to reduce the risk of falling among elderly people living in the community.
Mary E. Tinetti,Dorothy I. Baker,Gail McAvay,Elizabeth B. Claus,Patricia Garrett,Margaret Gottschalk,Marie L. Koch,Kathryn Trainor,Ralph I. Horwitz +8 more
TL;DR: The multiple-risk-factor intervention strategy resulted in a significant reduction in the risk of falling among elderly persons in the community and among persons who had the targeted risk factors for falling, as compared with the control group.
Journal ArticleDOI
Effect of computerized physician order entry and a team intervention on prevention of serious medication errors.
David W. Bates,Lucian L. Leape,David J. Cullen,Nan M. Laird,Laura A. Petersen,Jonathan M. Teich,Elizabeth Burdick,Mairead L. Hickey,Sharon Kleefield,Brian T. Shea,Martha Vander Vliet,Diane L. Seger +11 more
TL;DR: Physician computer order entry decreased the rate of nonintercepted serious medication errors by more than half, although this decrease was larger for potential ADEs than for errors that actually resulted in an ADE.
Journal ArticleDOI
Error in Medicine
TL;DR: Evidence from a number of sources indicates that a substantial number of patients suffer treatment-caused injuries while in the hospital, and inappropriate use of drugs was the leading cause of injuries.
Journal ArticleDOI
Pharmacist participation on physician rounds and adverse drug events in the intensive care unit.
Lucian L. Leape,David J. Cullen,Margaret D. Clapp,Elisabeth Burdick,Harold J. Demonaco,Jeanette Ives Erickson,David W. Bates +6 more
TL;DR: The presence of a pharmacist on rounds as a full member of the patient care team in a medical ICU was associated with a substantially lower rate of ADEs caused by prescribing errors.