Extubation failure in the very preterm infant
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TLDR
any very preterm infants require assisted ventilation and keeping such infants extubated will decrease lung injury and improve long-term pulmonary and perhaps even neurologic outcomes.Abstract:
any very preterm infants require assisted ventilation After resolution of their initial pulmonary dysfunction, when extubated they are at risk of failure due to poor respiratory drive, atelectasis, residual pulmonary function abnormalities, or intercurrent illness Keeping such infants extubated will decrease lung injury and improve long-term pulmonary and perhaps even neurologic outcomes On the other hand, if failure of extubation could be accurately predicted, then extubation could be deferred and the trauma of reintubation after a brief failed extubation, with increased work of breathing, hypoventilation, and respiratory acidosis, could be avoidedread more
Citations
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Stephen W. Reddel,Stephen W. Reddel,Robert A. Ouvrier,Robert A. Ouvrier,Garth A. Nicholson,Garth A. Nicholson,Ines Dierick,Joy Irobi,Vincent Timmerman,Monique M. Ryan +9 more
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Book ChapterDOI
Chapter 161 - Arthrogryposes (Multiple Congenital Contractures)
TL;DR: This chapter suggests a clinical approach to diagnosis including important elements of pregnancy, delivery, and family history, physical examination, and natural history, as well as multiple tables help the reader with the differential diagnosis.
References
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Journal ArticleDOI
Caffeine Therapy for Apnea of Prematurity
Barbara Schmidt,Robin S. Roberts,Peter G Davis,Lex W. Doyle,Keith J. Barrington,Arne Ohlsson,Alfonso Solimano,Win Tin +7 more
TL;DR: Caffeine therapy for apnea of prematurity reduces the rate of bronchopulmonary dysplasia in infants with very low birth weight and reduced weight gain temporarily.
Journal ArticleDOI
Long-Term Effects of Caffeine Therapy for Apnea of Prematurity
Barbara Schmidt,Robin S. Roberts,Peter G Davis,Lex W. Doyle,Keith J. Barrington,Arne Ohlsson,Alfonso Solimano,Win Tin +7 more
TL;DR: Caffeine therapy for apnea of prematurity improves the rate of survival without neurodevelopmental disability at 18 to 21 months in infants with very low birth weight.
Journal ArticleDOI
Randomized trial of nasal synchronized intermittent mandatory ventilation compared with continuous positive airway pressure after extubation of very low birth weight infants.
TL;DR: In this article, a study was conducted to determine whether noninvasive, nasal synchronized intermittent mandatory ventilation (nSIMV) improves the likelihood that very low birth weight infants will be successfully extubated.
Journal ArticleDOI
A Randomized Controlled Trial of Post-extubation Bubble Continuous Positive Airway Pressure Versus Infant Flow Driver Continuous Positive Airway Pressure in Preterm Infants with Respiratory Distress Syndrome
TL;DR: B Bubble CPAP is as effective as IFD CPAP in the post-extubation management of infants with RDS; however, in infants ventilated for < or = 14 days, bubble CP AP is associated with a significantly higher rate of successful extubation and a significantly reduced duration of CPAP support.