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Showing papers in "The Journal of Pediatrics in 2009"


Journal ArticleDOI
TL;DR: Prematurity is associated with long-term neurodevelopmental consequences, with risks increasing as gestation decreases, even in infants born at 34 to 36 weeks gestation.

418 citations




Journal ArticleDOI
TL;DR: Clinical neonatal seizures in the setting of birth asphyxia are associated with worse neurodevelopmental outcome, independent of the severity of hypoxic-ischemic brain injury.

342 citations


Journal ArticleDOI
TL;DR: Results from a nationally representative sample of US adolescents indicate that higher sugar-sweetened beverage consumption is associated with higher serum uric acid levels and systolic blood pressure, which may lead to downstream adverse health outcomes.

340 citations


Journal ArticleDOI
TL;DR: This study detected no difference in efficacy between lansoprazole and placebo for symptoms attributed to GERD in infants age 1 to 12 months.

321 citations


Journal ArticleDOI
TL;DR: Pulmonary abnormalities are common in infants and young children with CF and relate to neutrophilic inflammation and infection with P. aeruginosa, a clinically relevant endpoint that could be used for intervention trials that commence soon after CF is diagnosed after NBS.

318 citations


Journal ArticleDOI
TL;DR: A meta-analytic review of studies that examine the impact of violent media on aggressive behavior provided little support for the hypothesis that media violence is associated with higher aggression, and it cannot be concluded at this time thatMedia violence presents a significant public health risk.

300 citations


Journal ArticleDOI
TL;DR: Activity-promoting video games have the potential to increase movement and energy expenditure in children and adults.

294 citations


Journal ArticleDOI
TL;DR: A simplified ETV Success Score was devised that closely approximates the predicted probability of ETV success and can be accurately identified and spared the long-term complications of CSF shunting.

290 citations


Journal ArticleDOI
TL;DR: AP is common in school-age children and is associated with worse quality of life, psychological co-morbidities, school absenteeism, and parental work absences.

Journal ArticleDOI
TL;DR: In this article, the authors defined current frequency of prenatal detection of congenital heart disease (CHD), factors affecting prenatal detection, and its influence on postnatal course, and used logistic regression to analyze maternal, fetal, and prenatal-care provider risk factors for prenatal diagnosis.

Journal ArticleDOI
TL;DR: The authors examined the multivariate nature of risk factors for youth violence including delinquent peer associations, exposure to domestic violence in the home, family conflict, neighborhood stress, antisocial personality traits, depression level, and exposure to television and video game violence.

Journal ArticleDOI
TL;DR: The results strongly suggest that a locus on 8q24 is involved in the pathogenesis of NSCL/P, and this previous report acts as a de novo replication for the independent observation outlined here.

Journal ArticleDOI
TL;DR: It is demonstrated that childhood constipation has a significant impact on the use and cost of medical care services, and the estimated cost per year is 3 times than that in children without constipation, which likely is an underestimate of the actual burden of Childhood constipation.

Journal ArticleDOI
TL;DR: Data suggest that chronic sildenafil therapy is well-tolerated, safe, and effective for infants with PH and CLD.

Journal ArticleDOI
TL;DR: There is a delay of about 2.5 years between onset of DMD symptoms and the time of definitive diagnosis, unchanged over the previous 2 decades, which results in lost opportunities for timely genetic counseling and initiation of corticosteroid treatment.


Journal ArticleDOI
TL;DR: In this article, the role of breast milk in the development of early onset inflammatory bowel disease (IBD) was assessed with a systematic review, finding that breast milk exposure had a significant protective effect (OR, 0.69; 95% CI, 051-0.94; P =.02) in developing early onset IBD.

Journal ArticleDOI
TL;DR: IV sildenafil was well tolerated, and acute and sustained improvements in oxygenation were noted in those neonates who received the higher infusion doses.

Journal ArticleDOI
TL;DR: Although much progress has been made over the years in understanding the causes and mechanisms of altered neonatal glucose metabolism, the long-term consequences and the threshold values that may cause injury remain unknown.

Journal ArticleDOI
TL;DR: PICU VAP is associated with increased morbidity and mortality rates, and a multidisciplinary improvement team can implement a sustainable pediatric-specific VAP prevention bundle, resulting in VAP rate reduction.

Journal ArticleDOI
TL;DR: Newborns in China are ubiquitously exposed to phthalates; significantly higher phthalate levels were detected in LBW cases compared with controls and in utero DBP and DEHP exposures were associated with LBW in a dose-dependent manner.


Journal ArticleDOI
TL;DR: There is inadequate evidence that ABI has better outcomes than standard care for children with autism, and Appropriately powered clinical trials with broader outcomes are required.

Journal ArticleDOI
TL;DR: Serum 25-hydroxyvitamin D was measured in 128 youth with type 1 diabetes mellitus and it was found that less than 25% of the patients were vitamin D sufficient.

Journal ArticleDOI
TL;DR: In girls, academic achievement was associated with vigorous physical activity and not mediated by fitness, whereas in boys only fitness was associatedWith academic achievement, and the role of fitness herein is investigated.

Journal ArticleDOI
TL;DR: The term CFTR-related metabolic syndrome (CRMS) is proposed to describe infants identified by hypertrypsinogenemia on NBS who have sweat chloride values <60 mmol/L and up to 2 CFTR mutations, at least 1 of which is not clearly categorized as a "CF-causing mutation," thus they do not meet CF Foundation guidelines for the diagnosis of CF.

Journal ArticleDOI
TL;DR: Although mean EEEP levels were similar in NCPAP+6 and HFNC, tachypnea developed as flow diminished, and this system apparently cannot predict EEEP, because of interpatient and intrapatient variation.

Journal ArticleDOI
TL;DR: These curves represent waist and lipid percentiles for US children and adolescents, with identification of values that transition to adult abnormalities, and could be used conditionally for both epidemiological and possibly clinical applications, although they need to be validated against longitudinal data.