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Failure to complete performance-based measures is associated with poor health status and an increased risk of death

TLDR
The aim of the study was to establish whether the use of antipsychotic medication in elderly people with dementia is aversive to their quality of life and promote well-being.
Abstract
design, execution, analysis and interpretation of data, or preparation of the study. ALASTAIR MACDONALD1∗, DIMITRIOS ADAMIS2, ADRIAN TRELOAR2, FINBARR MARTIN3 1Institute of Psychiatry, Psychological Medicine, London, UK Email: alastair.macdonald@iop.kcl.ac.uk 2Oxleas NHS Trust, Old Age Psychiatry, London, UK 3Guy’s and St Thomas’ NHS Foundation Trust, Elderly Care Unit, London, UK ∗To whom correspondence should be addressed

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Journal ArticleDOI

Operationalization of Frailty Using Eight Commonly Used Scales and Comparison of Their Ability to Predict All‐Cause Mortality

TL;DR: To operationalize frailty using eight scales and to compare their content validity, feasibility, prevalence estimates of frailty, and ability to predict all‐cause mortality, it is shown that the former are more reliable than the latter.
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The impact of frailty on outcomes after cardiac surgery: A systematic review

TL;DR: Patients deemed frail, determined using an objective assessment tool, have a higher likelihood of experiencing mortality, morbidity, functional decline, and MACCE following cardiac surgery, regardless of definition.
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How should we grade frailty in nursing home patients

TL;DR: Frailty is a robust concept and however defined, elderly people who are frail have worse outcomes than those who are not frail and Random combinations of 15 variables used to make up alternate 5-item Frail-CHS definitions showed any stratification based on 5 variables allowed tertiles of risk to be discriminated.
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Frailty in primary care: a review of its conceptualization and implications for practice

TL;DR: This review seeks to address how frailty is recognised and managed, especially in the realm of primary care, including tools to identify frailty in the primary care setting.
Journal ArticleDOI

Functional dependencies among the elderly on hemodialysis.

TL;DR: This study shows that the disability in self-care is common among older patients on hemodialysis and strategies are needed to routinely identify those older dialysis patients at risk of functional impairment and to limit their disabilities.
References
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Journal ArticleDOI

Quantitative and Qualitative Alterations of Acute-phase Proteins in Healthy Elderly Persons

TL;DR: Findings suggest that both quantitative and qualitative alterations of acute-phase proteins occur with physiological ageing in humans.
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Human C-reactive protein increases cerebral infarct size after middle cerebral artery occlusion in adult rats.

TL;DR: It is shown that adult rats subjected to middle cerebral artery occlusion and then treated with human CRP similarly developed significantly larger cerebral infarcts compared with control subjects receiving human serum albumin.
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Different C-reactive protein kinetics in post-operative hip-fractured geriatric patients with and without complications.

TL;DR: CRP measurement in elderly patients operated for hip fracture may be valuable in assessing and monitoring complications, and was calculated for patients with complications.
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Plasma insulin growth factor-1 and incident delirium in older people.

TL;DR: A variety of demographic and clinical variables are acknowledged as risk factors for delirium; a syndrome thought to be mediated by abnormalities in a wide range of neurotransmitters.
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