Journal ArticleDOI
Feather follicle epithelium: a source of enveloped and infectious cell-free herpesvirus from Marek's disease.
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This article is published in Avian Diseases.The article was published on 1970-05-01. It has received 330 citations till now. The article focuses on the topics: Marek's disease & Mardivirus.read more
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Journal ArticleDOI
Transplantable Marek's Disease Lymphomas. I. Growth Characteristics During Development in Two Inbred Lines of Chickens"
Coleman Rm,Schierman Lw +1 more
TL;DR: A change in the cellular composition during a particular passage for both lymphomas, as indicated by marked increases in the percentage of cells possessing a MD tumor-associated surface antigen (MATSA), suggests that each arose as a result of the emergence and selection of a highly malignant clone of cells.
Journal ArticleDOI
Evaluation of factors influencing replication of serotype 1 Marek's disease vaccines in the chicken lung.
Isabel M. Gimeno,Aneg L. Cortes +1 more
TL;DR: It was shown that HP vaccines tend to replicate better than LP vaccines in the lung; and vaccine replication in the lungs within the first 10 days of age was affected by the age/route of inoculation but not by the dose of vaccine administered.
Journal ArticleDOI
Quail Cell Lines Supporting Replication of Marek's Disease Virus Serotype 1 and 2 and Herpesvirus of Turkeys
Xinhui Li,Karel A. Schat +1 more
TL;DR: Two recently developed cell lines, CU447 and CU453, developed from methylcholanthrene-induced tumors in Japanese quail, were examined for their suitability to propagate the three serotypes of Marek's disease virus.
Journal ArticleDOI
Selection of a Recombinant Marek's Disease Virus In Vivo Through Expression of the Marek's EcoRI-Q (Meq)–Encoded Oncoprotein: Characterization of an rMd5-Based Mutant Expressing the Meq of Strain RB-1B
Pankaj Kumar,Huimin Dong,Dawn Lenihan,Syamsundar Gaddamanugu,Upendra K. Katneni,Shireen A. R. Shaikh,Phaedra Tavlarides-Hontz,Sanjay M. Reddy,Wachen Peters,Mark S. Parcells +9 more
TL;DR: The results suggest that a recombinant MDV can be selected on the basis of oncogenicity; changes in Meq sequence seem to affect tumor composition and the ability to establish cell lines; and in addition to meq, other genomic loci affect MDV pathogenicity and oncogenesis.
Book ChapterDOI
The molecular biology of lymphotropic herpesviruses.
TL;DR: This chapter discusses the molecular biology of the three prototypic viruses—Marek's disease virus, Herpesvirus saimiri, and EBV and provides an overview of the relationship of these viruses to their hosts in vitro.