Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance.
Kyungwon Lee,Ki Hyung Park,Seok Hoon Jeong,Hwan Sub Lim,Jong Hee Shin,Dongeun Yong,Gyoung Yim Ha,Yunsop Chong +7 more
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In this article, the authors analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory and found that the following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%), expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40Abstract:
Monitoring temporal trends of antimicrobial resistance can provide useful information for the empirical selection of antimicrobial agents to treat infected patients and for the control of nosocomial infections. In this study, we analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory. The following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%), expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40%). Moreover, gradual increases in vancomycin-resistant Enterococcus faecium (20%), cefoxitin-resistant E. coli (10%) and K. pneumoniae (23%), and imipenem-resistant P. aeruginosa (20%) and Acinetobacter spp. (13%) were also observed. The resistance rates of Acinetobacter spp. to most antimicrobial agents at hospitals and at the commercial laboratory were similar. Among the Acinetobacter spp. isolated at a tertiary-care hospital, 46.2% were multidrug-resistant to 9-12 of 13 antimicrobial agents, and 18.3% were panresistant. The exclusion of duplicate isolates at a tertiary-care hospital significantly lowered the proportion of oxacillin-resistant S. aureus, vancomycin-resistant E. faecium, and fluoroquinolone-resistant E. coli.read more
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Global Challenge of Multidrug-Resistant Acinetobacter baumannii
Federico Perez,Andrea M. Hujer,Kristine M. Hujer,Brooke K. Decker,Philip N. Rather,Robert A. Bonomo,Robert A. Bonomo +6 more
TL;DR: This review summarizes the worldwide emergence of antibiotic-resistant A. baumannii as a nosocomial pathogen and focuses on its mechanisms of resistance against selected antibiotics.
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Dissemination of 16S rRNA methylase-mediated highly amikacin-resistant isolates of Klebsiella pneumoniae and Acinetobacter baumannii in Korea
Hyukmin Lee,Dongeun Yong,Jong Hwa Yum,Kyoung Ho Roh,Kyungwon Lee,Kunikazu Yamane,Yoshichika Arakawa,Yunsop Chong +7 more
TL;DR: 16S rRNA methylase-producing isolates of Gram-negative bacilli isolated in 2003 and 2005 were highly resistant to arbekacin and amikacin, and were mostly coresistant to levofloxacin.
Journal ArticleDOI
Epidemiology of carbapenem resistant Enterobacteriaceae (CRE) during 2000-2012 in Asia
TL;DR: Given the fact that the prevalence of CRE was increasing during the past decade, it is urgent for regional surveillance worldwide, carry out more effective antibiotic stewardship and infection control measures to prevent further spread of carbapenem resistance in Enterobacteriaceae.
Journal ArticleDOI
Update on Antibacterial Resistance in Low-Income Countries: FactorsFavoring the Emergence of Resistance
Jordi Vila,Tibor Pál +1 more
TL;DR: The current antimicrobial resistance in different microorganisms from different countries as well as the factors contributing to the emergence and spread of resistance in developing countries will be reviewed.
Journal ArticleDOI
High prevalence of ceftazidime-resistant Klebsiella pneumoniae and increase of imipenem-resistant Pseudomonas aeruginosa and Acinetobacter spp. in Korea: a KONSAR program in 2004.
Kyungwon Lee,Chang Hyun Lim,Ji Hyun Cho,Wee Gyo Lee,Young Uh,Hwi Jun Kim,Dongeun Yong,Yunsop Chong +7 more
TL;DR: In this paper, susceptibility test data generated in 2004 by KONSAR group hospitals were analyzed and compared to those at a commercial laboratory, and the mean resistance rates of significant antimicrobial-organism combinations in hospitals were: oxacillin-resistant S. aureus (68%), oxaclin-resistant (penicillin- nonsusceptible) Streptococcus pneumoniae (68), vancomycin-resistant E. coli, cefoxitin- resistant E. faecium, and imipenem-resistant Acinetobacter
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