Journal ArticleDOI
γ-Glutamyl transferase of swine kidney
F.H. Leibach,Francis Binkley +1 more
TLDR
An enzyme responsible for the hydrolysis of γ-glutamylnaphthylamide was separated from renal tissue and was found to be not influenced in its activity by the addition of acceptors.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1968-01-01. It has received 30 citations till now. The article focuses on the topics: Sephadex & Enzyme.read more
Citations
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Journal ArticleDOI
Interaction of γ-Glutamyl Transpeptidase with Amino Acids, Dipeptides, and Derivatives and Analogs of Glutathione
Suresh S. Tate,Alton Meister +1 more
TL;DR: In this article, a rat kidney γ-glutamyl transpeptidase was examined with respect to its γglutamide donor and acceptor specificities.
Journal ArticleDOI
γ-Glutamyltransferase in kidney brush border membranes
TL;DR: This study was undertaken to determine if y-glutamyltransferase could be demonstrated in brush border fractions, and was interested in enzymatic reactions which could function in a transport process.
Journal ArticleDOI
Identity of maleate-stimulated glutaminase with gamma-glutamyl transpeptidase in rat kidney.
TL;DR: The evidence reported here and earlier work in this laboratory strongly support the conclusion that maleate-stimulated glutaminase activity is a catalytic function of gamma-glutamyl transpeptidase.
Journal ArticleDOI
Comparison of the size and physical properties of gamma-glutamyltranspeptidase purified from rat kidney following solubilization with papain or with Triton X-100.
TL;DR: Data suggest that a peptide in the larger subunit of gamma-glutamyltranspeptidase is responsible for its binding to Triton micelles and probably for holding the enzyme in the brush border membrane.
Book ChapterDOI
Glutathione metabolism and some possible functions of glutathione in the nervous system.
TL;DR: The detection of neurological disorders in patients with inherited deficiencies in glutathione synthesis indicates the importance of this tripeptide in brain function.
References
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Journal ArticleDOI
Disc electrophoresis – ii method and application to human serum proteins*
TL;DR: The technique of disc electrophoresis has been presented, including a discussion of the technical variables with special reference to the separation of protein fractions of normal human serum.
Journal ArticleDOI
A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures
Robert G. Martin,Bruce N. Ames +1 more
TL;DR: Sucrose gradient centrifugation is found to be a suitable method for determining sedimentation coefficients of enzymes in protein mixtures and the sedimentation behavior of several of the enzymes in the pathway of histidine biosynthesis in S. typhimurium has been determined.
Journal ArticleDOI
Disc electrophoresis-i background and theory*
TL;DR: Some mechanisms that provide a rationale for the resolution afforded by zone electrophoresis in many gels will be detailed; the theory of some new modifications of zone electophoresis that have been designed to take maximum advantage of these mechanisms will be developed.