Genome mining of mycosporine-like amino acid (MAA) synthesizing and non-synthesizing cyanobacteria: A bioinformatics study.
TLDR
The present study provides a first insight into the genes of cyanobacteria involved in MAA biosynthesis and widens the field of research for molecular, bioinformatics and phylogenetic analysis of these evolutionary and industrially important compounds.About:
This article is published in Genomics.The article was published on 2010-02-01 and is currently open access. It has received 110 citations till now. The article focuses on the topics: Anabaena variabilis.read more
Citations
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Microbial ultraviolet sunscreens
Qunjie Gao,Ferran Garcia-Pichel +1 more
TL;DR: The current understanding of microbial 'sunscreen' compounds, including scytonemin, the mycosporines and the naphthalene-based melanins are described, which have led to the discovery of new classes of compounds, new metabolic pathways, a deeperUnderstanding of microbial photobiology and the potential for dermatological or biomedical applications.
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The Genetic and Molecular Basis for Sunscreen Biosynthesis in Cyanobacteria
TL;DR: The identification of a MAA biosynthetic gene cluster in a cyanobacterium and the discovery of analogous pathways in other sequenced organisms are reported.
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Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
TL;DR: The structure and physicochemical properties of MAAs are described, including the recently discovered compounds and the modern methods used for their isolation and identification, updating previous reviews.
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Biotechnological applications of extremophiles, extremozymes and extremolytes
TL;DR: An overview of extremophile ecology is provided, and the most recent applications of microbial extremophiles and the extremozymes and extremolytes they produce to biotechnology are reviewed.
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Photoprotective compounds from marine organisms
TL;DR: There is a need for extensive work to explore the photoprotective role of various UV-absorbing compounds from marine habitats so that a range of biotechnological and pharmaceutical applications can be found.
References
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Related Papers (5)
The Genetic and Molecular Basis for Sunscreen Biosynthesis in Cyanobacteria
Mycosporine-Like Amino Acids and Related Gadusols: Biosynthesis, Accumulation, and UV-Protective Functions in Aquatic Organisms
Mycosporines and mycosporine-like amino acids: UV protectants or multipurpose secondary metabolites?
Aharon Oren,Nina Gunde-Cimerman +1 more