Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden.
TLDR
It is concluded that hematological changes are common complications encountered in severe malaria, but they are not related to the clinical outcome.Abstract:
Objective: To study some hematological parameters in adult patients with complicated severe malaria and their relations to clinical outcome.
Materials and Methods: This was a prospective study, including 77 patients from Aden Governorate with complicated severe malaria over the course of 2 years (2010-2011).
Results: The common form of severe malaria in Aden was cerebral malaria (25.9%), followed by renal failure (18.2%), severe anemia (16.9%), and hepatitis (14.3%), with a case fatality rate of 7.8%. Hemoglobin concentration was significantly different among the various complications of severe malaria, while platelet and white blood cell counts did not show such differences. The mean age was older among patients that died. Hematological parameters did not significantly differ among dead or surviving patients. Thrombocytopenia was seen in 42.9% of patients and 18.2% of these had platelet counts of <50.0x109/L. However, none of them developed bleeding.
Conclusion: This study concluded that hematological changes are common complications encountered in severe malaria, but they are not related to the clinical outcome.
Conflict of interest:None declared.read more
Citations
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TL;DR: Patients infected with malaria exhibited important changes in most of haematological parameters with low platelet, WBCs, and lymphocyte counts being the most important predictors of malaria infection.
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Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen.
TL;DR: Hematological and liver dysfunctions measured parameters were seen associated with moderate and severe parasitaemia infection, and could be indicator of malaria in endemic regions.
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The application of physiologically based pharmacokinetic modelling to assess the impact of antiretroviral-mediated drug-drug interactions on piperaquine antimalarial therapy during pregnancy.
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Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital.
TL;DR: Leukemia, anemia, and thrombocytopenia were found to be significantly associated with malaria and were all estimated to be specific for the diagnosis of malaria.
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Uncomplicated falciparum malaria among schoolchildren in Bajil district of Hodeidah governorate, west of Yemen: association with anaemia and underweight.
Talal S. Alwajeeh,Rashad Abdul-Ghani,Rashad Abdul-Ghani,Amal Farahat Allam,Hoda Fahmy Farag,Safia Saleh Khalil,Amel Youssef Shehab,Mona H El-Sayad,Raed A. Alharbi,Shaia Saleh R. Almalki,Ahmed A. Azazy +10 more
TL;DR: Asymptomatic falciparum malaria is prevalent among schoolchildren in Bajil district of Hodeidah Governorate, with predominance of low parasitaemic infections and significant association with mild anaemia and underweight and further studies among children with severe malaria and those with high parasite densities are recommended.
References
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