Journal ArticleDOI
Hepatitis B virus and primary hepatocellular carcinoma: treatment of HBV carriers with Phyllanthus amarus.
TLDR
Preliminary results in human carriers treated orally with P. amarus for 1 month indicated that approximately 60% of the carriers lost HBV during the observation period.About:
This article is published in Vaccine.The article was published on 1990-03-01. It has received 57 citations till now. The article focuses on the topics: Hepatitis B virus & Woodchuck hepatitis virus.read more
Citations
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Journal ArticleDOI
Antioxidant properties of Phyllanthus amarus extracts as affected by different drying methods
Yau Yan Lim,Johannes Murtijaya +1 more
TL;DR: The total phenolic content (TPC) and antioxidant activity of fresh and dried Phyllanthus amarus plant materials were evaluated using the Folin-Ciocalteau method, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity and ferric reducing antioxidant power (FRAP) assays.
Journal ArticleDOI
Medicinal plants and cancer chemoprevention.
Avni G. Desai,Ghulam Nabi Qazi,Ramesh K. Ganju,Mahmoud El-Tamer,Jaswant Singh,Ajit Kumar Saxena,Yashbir S. Bedi,Subhash C. Taneja,Hari K. Bhat +8 more
TL;DR: This review will focus on the various plant-derived chemical compounds that have, in recent years, shown promise as anticancer agents and will outline their potential mechanism of action.
Journal ArticleDOI
Phyllanthus amarus: Ethnomedicinal uses, phytochemistry and pharmacology: A review
TL;DR: The present review summarizes information concerning the morphology, ecology, ethnopharmacology, phytochemistry, biological activities, clinical applications and toxicological reports of P. amarus to provide sufficient baseline information for future works and commercial exploitation.
Journal Article
Andrographis paniculata: a review of pharmacological activities and clinical effects.
TL;DR: Kutkins are group of pharmacologically active compounds present in Picrorhiza kurroa Royle (Scrophulariaceae).
Journal ArticleDOI
Antitumour and anticarcinogenic activity of Phyllanthus amarus extract.
N. V. Rajeshkumar,K.L. Joy,Girija Kuttan,Russel S. Ramsewak,Muraleedharan G. Nair,Ramadasan Kuttan +5 more
TL;DR: Aqueous extract of Phyllanthus amarus treatment exhibited potent anticarcinogenic activity against 20-methylcholanthrene (20-MC) induced sarcoma development and increased the survival of tumour harboring mice.
References
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Book ChapterDOI
Nonparametric Estimation from Incomplete Observations
Edward L. Kaplan,Paul Meier +1 more
TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Journal ArticleDOI
A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks.
TL;DR: Particles with properties similar to those associated with human hepatitis B were found in serum from woodchucks with chronic hepatitis and hepatocellular carcinoma and it is suggested that woodchuck hepatitis virus is a second member of a novel class of viruses represented by thehuman hepatitis B virus.
Journal ArticleDOI
Effect of phyllanthus amarus on chronic carriers of hepatitis b virus
Sadras Panchatcharam Thyagarajan,T. Thirunalasundari,S Subramanian,P.S. Venkateswaran,B. S. Blumberg +4 more
TL;DR: In a preliminary study, carriers of hepatitis B virus were treated with a preparation of the plant Phyllanthus amarus for 30 days and 22 of 37 treated patients had lost hepatitis B surface antigen when tested 15-20 days after the end of the treatment.
Effects of an extract from Phyllanthus niruri on hepatitis B and woodchuck hepatitis viruses: In vitro and in vivo studies (antiviral agent/Marmota monax/DNA polymerase/hepatitis B surface antigen/woodchuck hepatitis surface antigen)
TL;DR: An aqueous extract of the plant Phyllanthus niruri was tested for antiviral activity in woodchucks (Marmota monax) as discussed by the authors, and the extract was effective when adminis- tered i.p. in three out of four animals in reducing and within 3-6 weeks eliminating both surface antigen titer and DNA polymerase activity in serum.
Journal ArticleDOI
Effects of an extract from Phyllanthus niruri on hepatitis B and woodchuck hepatitis viruses: in vitro and in vivo studies.
TL;DR: In animals recently infected with WHV, the extract was effective when administered i.p. in three out of four animals in reducing and within 3-6 weeks eliminating both the surface antigen titer and DNA polymerase activity in serum.