Journal ArticleDOI
High-speed combinatorial synthesis utilizing microwave irradiation.
TLDR
The impressive speed combined with the unmatched control over reaction parameters justifies the growing interest in this application of microwave heating.About:
This article is published in Current Opinion in Chemical Biology.The article was published on 2002-06-01. It has received 251 citations till now. The article focuses on the topics: Combinatorial Chemistry Techniques.read more
Citations
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Journal ArticleDOI
Controlled microwave heating in modern organic synthesis.
TL;DR: This Review highlights recent applications of controlled microwave heating in modern organic synthesis, and discusses some of the underlying phenomena and issues involved.
Journal ArticleDOI
Microwaves in organic synthesis. thermal and non-thermal microwave effects
TL;DR: An overview of the thermal effects and the current state of non-thermal microwave effects is presented in this critical review along with a view on how these phenomena can be effectively used in organic synthesis.
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‘Click’ Chemistry in Polymer and Materials Science
TL;DR: The metal catalyzed azide/alkyne "click" reaction (a variation of the Huisgen 1,3-dipolar cycloaddition reaction between terminal acetylenes and azides) represents an important contribution towards this endeavor.
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Ionic liquids in heterocyclic synthesis.
TL;DR: Ionic Liquids Presented in This Review 2020 3.1.
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Microwave-assisted organic synthesis and transformations using benign reaction media.
TL;DR: The use of emerging microwave-assisted chemistry techniques in conjunction with greener reaction media is dramatically reducing chemical waste and reaction times in several organic syntheses and chemical transformations.
References
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Journal ArticleDOI
Microwave assisted organic synthesis-a review
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A tentative rationalization of microwave effects in organic synthesis according to the reaction medium, and mechanistic considerations
Laurence Perreux,André Loupy +1 more
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Dielectric parameters relevant to microwave dielectric heating
TL;DR: In this paper, the basic theory underlying microwave dielectric heating and collates the data for a wide range of organic solvents which are commmonly used in microwave syntheses.
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Microwave-assisted high-speed chemistry: a new technique in drug discovery.
Mats Larhed,Anders Hallberg +1 more
TL;DR: It is believed that the time saved by using focused microwaves is potentially important in traditional organic synthesis but could be of even greater importance in high-speed combinatorial and medicinal chemistry.
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Functionalized Polymers—Emerging Versatile Tools for Solution-Phase Chemistry and Automated Parallel Synthesis
TL;DR: It has been demonstrated that complex natural products like the alkaloids +/-)-oxomaritidine and (+/-)-epimaritidine can be prepared by a sequence of five and six consecutive polymer-assisted steps, respectively, and the potent analgesic compound (+/--epibatidine in twelve linear steps ten of which are based on functionalized polymers.