Journal ArticleDOI
Highly efficient, mild and chemo- and stereoselective synthesis of enaminones and enamino esters using silica supported perchloric acid under solvent-free conditions
Biswanath Das,Katta Venkateswarlu,Anjoy Majhi,Majjigapu Ravinder Reddy,Kuravallapalli Nagabhushana Reddy,Yerra Koteswara Rao,Krishnan Ravikumar,Balasubramanian Sridhar +7 more
TLDR
Silica supported perchloric acid (HClO 4 ·SiO 2 ) has been utilized as a heterogeneous recyclable catalyst for a highly efficient and chemo- and stereoselective conversion of β-dicarbonyl compounds by treatment with amines at room temperature into β-enaminones and β-ENamino esters under solvent-free conditions as discussed by the authors.Abstract:
Silica supported perchloric acid (HClO 4 ·SiO 2 ) has been utilized as a heterogeneous recyclable catalyst for a highly efficient and chemo- and stereoselective conversion of β-dicarbonyl compounds by treatment with amines at room temperature into β-enaminones and β-enamino esters under solvent-free conditions.read more
Citations
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Recent developments in solvent-free multicomponent reactions: a perfect synergy for eco-compatible organic synthesis
TL;DR: In this paper, the authors summarized the results reported mainly within the last 10 years, and it is quite clear from the growing number of emerging publications in this field that the possibility to utilize multicomponent technology allows reaction conditions to be accessed that are very valuable for organic synthesis.
Journal ArticleDOI
Silica supported perchloric acid (HClO4–SiO2): an efficient and recyclable heterogeneous catalyst for the one-pot synthesis of amidoalkyl naphthols
TL;DR: An efficient and direct protocol for the preparation of amidoalkyl naphthols employing a multi-component and one-pot condensation reaction of 2-naphthol, aromatic aldehydes, and acetonitrile or acetamide in the presence of silica supported perchloric acid under solvent, solvent-free, and microwave irradiation conditions is described in this paper.
Journal ArticleDOI
Perchloric acid and its salts: very powerful catalysts in organic chemistry
TL;DR: A comparison of ring-Opening Reactions and Multicomponent Reactions shows the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for humans and animals.
Journal ArticleDOI
A revision for the synthesis of β-enaminones in solvent free conditions: efficacy of different supported heteropoly acids as active and reusable catalysts
TL;DR: In this article, the performance of different supported heteropoly acids (HPAs) in the synthesis of β-enaminones and βenamino esters from various substituted amines and β-diketones or β-keto esters has been studied.
Journal ArticleDOI
Scope and limitations of HClO4–SiO2 as an extremely efficient, inexpensive, and reusable catalyst for chemoselective carbon–sulfur bond formation
TL;DR: In this article, perchloric acid adsorbed on silica gel (HClO4-SiO2) was used as a highly efficient, inexpensive and reusable catalyst for chemoselective carbon-sulfur bond formation by conjugate addition of thiols to α,β-unsaturated ketones under solvent-free conditions and at rt are reported.
References
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Perchloric acid adsorbed on silica gel as a new, highly efficient, and versatile catalyst for acetylation of phenols, thiols, alcohols, and amines
TL;DR: Perchloric acid adsorbed on silica gel efficiently catalyses acetylation of structurally diverse phenols, alcohols, thiols, and amines under solvent free conditions.
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Stereocontrolled synthesis of (+)-negamycin from an acyclic homoallylamine by 1,3-asymmetric induction
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Total synthesis and evaluation of (.+-.)-N-(tert-butoxycarbonyl)-CBI, (.+-.)-CBI-CDPI1, and (.+-.)-CBI-CDPI2: CC-1065 functional agents incorporating the equivalent 1,2,9,9a-tetrahydrocyclopropa[1,2-c]benz[1,2-e]indol-4-one (CBI) left-hand subunit
Dale L. Boger,Takayoshi Ishizaki,Ronald J. Wysocki,Stephen A. Munk,Paul A. Kitos,Oranart Suntornwat +5 more
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Gold catalysis in the reactions of 1,3-dicarbonyls with nucleophiles
TL;DR: A new efficient gold(III) catalysed synthesis of β-enaminones from 1,3-dicarbonyl compounds and ammonia/amines providing an attractive and environmental friendly alternative to the more vigorous reagents and drastic conditions of the existing methodologies is described.
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Chemo- and Diastereoselective Reduction of .beta.-Enamino Esters: A Convenient Synthesis of Both cis- and trans-.gamma.-Amino Alcohols and .beta.-Amino Esters
TL;DR: In this paper, the chemo-and diastereoselective reduction of β-enamino esters is described, with the use of inexpensive reagents Na/i-PrOH or NaHB(OAc) 3 /AcOH, respectively.