Histological Typing of tumours of the Central Nervous System
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TLDR
A histological classification of CNS Tumours is presented, highlighting the importance of knowing the carrier and removal status of canine coronavirus as a source of infection for humans.Abstract:
Introduction Histological Classification of CNS Tumours Definitions and Explanatory Notes Tumours of Neuroepithelial Tissue Astrocytic Tumours Ependymal Tumours Mixed Gliomas Choroid Plexus Tumours Neuroepithelial Tumours of Uncertain Origin Neuronal and Mixed Neuronal-Glial Tumours Pineal Parenchymal Tumours Embryonal Tumours Tumours of Cranial and Spinal Nerves Schwannoma Neurofibroma Malignant Peripheral Nerve Sheath Tumor Tumours of the Meninges Tumours of Menigothelial Cells Mesenchymal, Non-menigothelial Tumours Primary Melanocytic Lesions Lymphomas and Haemopoietic Neoplasms Germ Cell Tumours Cysts and Tumour-like Lesions Tumours of the Sellar Region Local Extensions from Regional Tumours Metastatic Tumours Unclassified Tumours Illustrations Subject Index Metat Cy Turead more
Citations
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Journal ArticleDOI
The 2007 WHO Classification of Tumours of the Central Nervous System
David N. Louis,Hiroko Ohgaki,Otmar D. Wiestler,Webster K. Cavenee,Peter C. Burger,Anne Jouvet,Bernd W. Scheithauer,Paul Kleihues +7 more
TL;DR: The fourth edition of the World Health Organization (WHO) classification of tumours of the central nervous system, published in 2007, lists several new entities, including angiocentric glioma, papillary glioneuronal tumour, rosette-forming glioneurs tumour of the fourth ventricle, Papillary tumourof the pineal region, pituicytoma and spindle cell oncocytoma of the adenohypophysis.
Journal ArticleDOI
The WHO Classification of Tumors of the Nervous System
Paul Kleihues,David N. Louis,Bernd W. Scheithauer,Lucy B. Rorke,Guido Reifenberger,Peter C. Burger,Webster K. Cavenee +6 more
TL;DR: The new World Health Organization (WHO) classification of nervous system tumors, published in 2000, emerged from a 1999 international consensus conference of neuropathologists, and new entities include chordoid glioma of the third ventricle, cerebellar liponeurocytoma, atypical teratoid/rhabdoid tumor, and perineurioma.
Journal ArticleDOI
Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas
Cairncross Jg,Keisuke Ueki,Magdalena C. Zlatescu,David K. Lisle,Dianne M. Finkelstein,Robert Hammond,Jonathan S. Silver,Paul Stark,David R. Macdonald,Yasushi Ino,David A. Ramsay,David N. Louis +11 more
TL;DR: Allelic loss (or loss of heterozygosity) of chromosome 1p is a statistically significant predictor of chemosensitivity, and combined loss involving chromosomes 1p and 19q is statistically significantly associated with both chemos sensitivity and longer recurrence-free survival after chemotherapy.
Journal ArticleDOI
Genetic Pathways to Primary and Secondary Glioblastoma
Hiroko Ohgaki,Paul Kleihues +1 more
TL;DR: Primary and secondary glioblastomas constitute distinct disease subtypes, affecting patients of different age and developing through different genetic pathways, and differ significantly in their pattern of promoter methylation and in expression profiles at RNA and protein levels.
Journal ArticleDOI
Angiogenesis in brain tumours
Rakesh K. Jain,Emmanuelle di Tomaso,Dan G. Duda,Jay S. Loeffler,A. Gregory Sorensen,Tracy T. Batchelor +5 more
TL;DR: Emerging preclinical and clinical data indicate that anti-VEGF therapies are potentially effective in glioblastoma and can transiently normalize tumour vessels, creating a window of opportunity for optimally combining chemotherapeutics and radiation.
References
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Journal ArticleDOI
The 2007 WHO Classification of Tumours of the Central Nervous System
David N. Louis,Hiroko Ohgaki,Otmar D. Wiestler,Webster K. Cavenee,Peter C. Burger,Anne Jouvet,Bernd W. Scheithauer,Paul Kleihues +7 more
TL;DR: The fourth edition of the World Health Organization (WHO) classification of tumours of the central nervous system, published in 2007, lists several new entities, including angiocentric glioma, papillary glioneuronal tumour, rosette-forming glioneurs tumour of the fourth ventricle, Papillary tumourof the pineal region, pituicytoma and spindle cell oncocytoma of the adenohypophysis.
Journal ArticleDOI
The WHO Classification of Tumors of the Nervous System
Paul Kleihues,David N. Louis,Bernd W. Scheithauer,Lucy B. Rorke,Guido Reifenberger,Peter C. Burger,Webster K. Cavenee +6 more
TL;DR: The new World Health Organization (WHO) classification of nervous system tumors, published in 2000, emerged from a 1999 international consensus conference of neuropathologists, and new entities include chordoid glioma of the third ventricle, cerebellar liponeurocytoma, atypical teratoid/rhabdoid tumor, and perineurioma.
Journal ArticleDOI
Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas
Cairncross Jg,Keisuke Ueki,Magdalena C. Zlatescu,David K. Lisle,Dianne M. Finkelstein,Robert Hammond,Jonathan S. Silver,Paul Stark,David R. Macdonald,Yasushi Ino,David A. Ramsay,David N. Louis +11 more
TL;DR: Allelic loss (or loss of heterozygosity) of chromosome 1p is a statistically significant predictor of chemosensitivity, and combined loss involving chromosomes 1p and 19q is statistically significantly associated with both chemos sensitivity and longer recurrence-free survival after chemotherapy.
Journal ArticleDOI
Genetic Pathways to Primary and Secondary Glioblastoma
Hiroko Ohgaki,Paul Kleihues +1 more
TL;DR: Primary and secondary glioblastomas constitute distinct disease subtypes, affecting patients of different age and developing through different genetic pathways, and differ significantly in their pattern of promoter methylation and in expression profiles at RNA and protein levels.
Journal ArticleDOI
Usefulness of diffusion-weighted MRI with echo-planar technique in the evaluation of cellularity in gliomas.
Takeshi Sugahara,Yukunori Korogi,Masato Kochi,Ichiro Ikushima,Yoshinori Shigematu,Toshinori Hirai,T. Okuda,Luxia Liang,Yulin Ge,Yasuyuki Komohara,Yukitaka Ushio,Mutsumasa Takahashi +11 more
TL;DR: Diffusion‐weighted MRI with EPI is a useful technique for assessing the tumor cellularity and grading of gliomas and is useful for the diagnosis and characterization ofgliomas.