Hormone replacement therapy in young women with primary ovarian insufficiency and early menopause.
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TLDR
To decrease morbidity associated with POI, it is recommended using HRT formulations that most closely mimic normal ovarian hormone production and continuing HRT until the normal age of natural menopause, ∼50 years.About:
This article is published in Fertility and Sterility.The article was published on 2016-12-01 and is currently open access. It has received 246 citations till now. The article focuses on the topics: Premature ovarian failure & Menopause.read more
Citations
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Journal ArticleDOI
The 2017 hormone therapy position statement of The North American Menopause Society.
JoAnn V. Pinkerton,Fernando Sánchez Aguirre,Jennifer Blake,Felicia Cosman,Howard N. Hodis,Susan Hoffstetter,Andrew M. Kaunitz,Sheryl A. Kingsberg,Pauline M. Maki,JoAnn E. Manson,Polly Marchbanks,Michael R. McClung,Lila E. Nachtigall,Lawrence M. Nelson,Diane Todd Pace,Robert L. Reid,Phillip M. Sarrel,Jan L. Shifren,Cynthia A. Stuenkel,Wulf H. Utian +19 more
TL;DR: Hormone therapy (HT) remains the most effective treatment for vasomotor symptoms and the genitourinary syndrome of menopause (GSM) and has been shown to prevent bone loss and fracture.
Journal ArticleDOI
Premature Ovarian Insufficiency - an update on recent advances in understanding and management
TL;DR: Ongoing research is clearly needed to allow pre-emptive identification of the at-risk population and to identify mechanisms that if addressed in a timely manner, can prolong ovarian function and physiology.
Journal ArticleDOI
Human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation improves ovarian function in rats with premature ovarian insufficiency (POI) at least partly through a paracrine mechanism
Li Ling,Xiushan Feng,Tianqin Wei,Yan Wang,Yaping Wang,Ziling Wang,Dongyuan Tang,Yanjing Luo,Zhengai Xiong +8 more
TL;DR: Human amnion-derived mesenchymal stem cells (hAD-MSCs) transplantation can improve ovarian function in rats with chemotherapy-induced POI at least partly through a paracrine mechanism.
Book ChapterDOI
Sex-Specific Physiology and Cardiovascular Disease.
TL;DR: This chapter addresses how understanding basic mechanisms of hormone responses, imaging diagnostics, and integration of genomics and proteomics has advanced diagnosis and improved outcomes for cardiovascular conditions, apart from those related to pregnancy that are more prevalent in women.
Journal ArticleDOI
Hypothalamic-Pituitary-Ovarian Axis Disorders Impacting Female Fertility.
TL;DR: Optimal evaluation and management of ovulation disorders is based on a careful analysis tailored to each patient, and currently available management options are reviewed.
References
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Journal ArticleDOI
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
Jacques E. Rossouw,Garnet L. Anderson,Ross L. Prentice,Andrea Z. LaCroix,Charles Kooperberg,Marcia L. Stefanick,Rebecca D. Jackson,Shirley A.A. Beresford,Barbara V. Howard,Karen C. Johnson,Jane Morley Kotchen,Judith K. Ockene +11 more
TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
Journal ArticleDOI
Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline
Michael F. Holick,Neil Binkley,Heike A. Bischoff-Ferrari,Catherine M. Gordon,David A. Hanley,Robert P. Heaney,M. Hassan Murad,Connie M. Weaver +7 more
TL;DR: Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recommended supplementation at suggested daily intake and tolerable upper limit levels, depending on age and clinical circumstances.
Journal Article
Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline (Journal of Clinical Endocrinology and Metabolism (2011) 96, (1911-1930))
Michael F. Holick,Neil Binkley,Heike A. Bischoff-Ferrari,Catherine M. Gordon,David A. Hanley,Robert P. Heaney,M. Hassan Murad,Connie M. Weaver +7 more
TL;DR: The Task Force as discussed by the authors provided guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency, based on systematic reviews of evidence and discussions during several conference calls and e-mail communications.
Journal ArticleDOI
Menopause and the risk of coronary heart disease in women.
Graham A. Colditz,Walter C. Willett,Meir J. Stampfer,Bernard Rosner,Frank E. Speizer,Charles H. Hennekens +5 more
TL;DR: Data suggest that, in contrast to a natural menopause, bilateral oophorectomy increases the risk of coronary heart disease, and this increase appears to be prevented by estrogen-replacement therapy.
Journal ArticleDOI
Incidence of premature ovarian failure.
TL;DR: To assess the occurrence of premature ovarian failure, the age-specific incidence rates of natural menopause were determined for a cohort of 1858 women born between 1928 and 1932, and the incidence increased greatly in the age group 40 to 44.
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The 2017 hormone therapy position statement of The North American Menopause Society.
JoAnn V. Pinkerton,Fernando Sánchez Aguirre,Jennifer Blake,Felicia Cosman,Howard N. Hodis,Susan Hoffstetter,Andrew M. Kaunitz,Sheryl A. Kingsberg,Pauline M. Maki,JoAnn E. Manson,Polly Marchbanks,Michael R. McClung,Lila E. Nachtigall,Lawrence M. Nelson,Diane Todd Pace,Robert L. Reid,Phillip M. Sarrel,Jan L. Shifren,Cynthia A. Stuenkel,Wulf H. Utian +19 more