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Journal ArticleDOI

Human and equine cardiovascular endocrinology: beware to compare

TLDR
Comparison between human and equine cardiac biomarker studies show important species differences, which can partly be explained by variations in physiology or pathophysiology.
Abstract
Cardiac biomarkers such as troponins and natriuretic peptides are routinely used in human medicine for the evaluation of myocardial damage and heart failure. Recently, these markers have also been introduced in veterinary medicine. Comparison between human and equine cardiac biomarker studies show i

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Citations
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Journal ArticleDOI

Cardiac troponin I as compared to troponin T for the detection of myocardial damage in horses

TL;DR: Despite large quantitative differences, cTtnI and cTnT are both useful for detection of myocardial damage in horses.

Serum cardiac troponin I concentrations in horses with cardiac diseases.

TL;DR: Cardiac troponin I is elevated in horses with myocardial disease and elevated to a lesser degree in some horses with structural heart disease or lone arrhythmias, and the association between cTnI concentration and survival was not clear.
Journal ArticleDOI

Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes.

TL;DR: Prolonged exercise in horses is associated with impaired LV diastolic function, and reduced ventricular filling persisted for 7–21 hours despite normalization of biochemical indicators of hydration status, indicating that the observed changes were not entirely related to altered preload conditions.
Patent

Biomarkers for osteoarthritis

TL;DR: In this paper, methods for evaluating osteoarthritis (OA), for example for diagnosing OA, to confirm a diagnosis of OA and to assess or prognose progression of OOA, determining the severity of a subject who has OA; and determining a subject's risk of developing OA in the future, as are arrays and kits that can be used to practice the methods.
Patent

Method for prediction of prognosis of sepsis

TL;DR: In this paper, a prediction method for the prognosis of sepsis comprising measuring an sCD14-ST level in a sample was proposed, which is a marker superior to procalcitonin.
References
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Journal ArticleDOI

Burden of valvular heart diseases: a population-based study.

TL;DR: In this paper, the authors assess the prevalence and effect of valve disease on overall survival in the general population and find that moderate or severe valve disease is common in this population and increase with age.
Journal Article

Burden of valvular heart diseases : a population-based study. Commentary

TL;DR: Moderate or severe valvular heart diseases are notably common in this population and increase with age and in the community, women are less often diagnosed than are men, which could indicate an important imbalance in view of the associated lower survival.
BookDOI

Cardiovascular Disease 2

TL;DR: It is suggested that GPIIb/IIIa receptor blockade as compared with direct inhibition of thrombin, does not inhibit intracellular CaH mobilization signal transduction.
Journal ArticleDOI

Plasma Natriuretic Peptide Levels and the Risk of Cardiovascular Events and Death

TL;DR: Peptide levels predicted the risk of death and cardiovascular events after adjustment for traditional risk factors and excess risk was apparent at natriuretic peptide levels well below current thresholds used to diagnose heart failure.
Journal ArticleDOI

Atrial fibrillation.

Rahul Wadke
TL;DR: The primary treatment of atrial fibrillation involves rate control, prevention of thromboembolic events and restoring the heart to sinus rhythm, which is achieved through pharmacological treatment and cardioversion.
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