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Journal ArticleDOI

Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats.

TLDR
An attempt has been made to evaluate the presence of hypoglycemic activity in the alcoholic extract of Aloe vera gel, which is believed to maintain the glucose homeostasis by controlling the carbohydrate metabolizing enzymes.
Abstract
In the present study an attempt has been made to evaluate the presence of hypoglycemic activity in the alcoholic extract of Aloe vera gel. Effects of oral administration of A. vera extract at a concentration of 200 and 300 mg/kg of body weight on (a) normal fasted rats, (b) oral glucose-loaded rats, and (c) streptozotocin-induced diabetic rats have been studied. A. vera extract maintain the glucose homeostasis by controlling the carbohydrate metabolizing enzymes.

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Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province).

TL;DR: Traditional medicine in the south-eastern Moroccan population has not only survived but has thrived in the transcultural environment and intermixture of many ethnic traditions and beliefs.
Journal ArticleDOI

An evaluation of the biological and toxicological properties of Aloe barbadensis (miller), Aloe vera.

TL;DR: A review of the botany, physical and chemical properties, and biological activities of the Aloe vera plant finds that it contains multiple constituents with potential biological and toxicological activities, yet the active components elude definition.
Journal ArticleDOI

Leads from Indian medicinal plants with hypoglycemic potentials

TL;DR: This article aims to provide a comprehensive review on various plant species from Indian biosphere and their constituents, which have been shown to display potent hypoglycemic activity.
Journal Article

Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats.

TL;DR: Results clearly show the antioxidant property of Aloe vera gel extract, which was also more effective than glibenclamide in restoring the values of these parameters.
Journal ArticleDOI

Animal models to test drugs with potential antidiabetic activity.

TL;DR: The available animal models of diabetes and some in vitro models which have been used as tools to investigate the mechanism of action of drugs with potential antidiabetic properties are reviewed to contribute to the researcher in the ethnopharmacology field to designs new strategies for the development of novel drugs to treat this serious condition.
References
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Journal Article

Protein Measurement with the Folin Phenol Reagent

TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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The Redox State of Free Nicotinamide-Adenine Dinucleotide in the Cytoplasm and Mitochondria of Rat Liver

TL;DR: The bearing of these findings on various problems, including the number of NAD(+)-NADH pools in liver cells; the applicability of the method to tissues other than liver; the transhydrogenase activity of glutamate dehydrogenase; the physiological significance of the difference of the redox states of mitochondria and cytoplasm; aspects of the regulation of theredox state of cell compartments; the steady-state concentration of mitochondrial oxaloacetate.
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Isolation of a virus from the pancreas of a child with diabetic ketoacidosis.

TL;DR: Both the clinical picture and animal studies suggested that the patient's diabetes was virus induced.
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Fructose-1,6-diphosphatase, phosphofructokinase and glucose-6-phosphate dehydrogenase from fermenting and non fermenting yeasts.

TL;DR: A remarkable difference in the sensitivity of the fructose-1,6-diphosphatase from both groups towards inhibition by AMP was observed, while the enzyme from aerobic yeasts showed different responses, inhibition ranging from 10% in Rhodotorula and Sporobolomyces, to 90% in Pichia.
Journal ArticleDOI

The control of glycogen metabolism in the liver.

TL;DR: In this paper, anesthetized fed rats were found to inactivate the liver phosphorylase in the liver of normal rats, but more often was without effect when effective in the diabetic animal.
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